Results 1 to 10 of about 333,455 (263)

Comprehensive analysis of transcriptome-wide m6A methylome in the anterior capsule of the lens of high myopia patients

open access: yesEpigenetics, 2021
To assess the m6A methylome in the anterior capsule of the lens of high myopia patients. MeRIP-seq and RNA-seq were performed to identify differences in the m6A methylomes and gene expression between anterior capsule of the lens of simple nuclear ...
Kai Wen   +4 more
doaj   +1 more source

Ti3C2 (MXene) nanosheets disrupt spermatogenesis in male mice mediated by the ATM/p53 signaling pathway

open access: yesBiology Direct, 2023
Background Two-dimensional ultrathin Ti3C2 nanosheets are increasingly being used in biomedical applications owing to their special physicochemical properties. But, the biological effects of its exposure on the reproductive system is still unclear.
Yang Wei   +9 more
doaj   +1 more source

The complete chloroplast genome sequence of Trollius macropetalus

open access: yesMitochondrial DNA. Part B. Resources, 2021
The complete chloroplast genome of Trollius macropetalus was sequenced in this study. It has a cyclic tetrad structure typical of angiosperms. The total length is 160,094 bp, including a large single copy region (LSC) with a length of 88,555 bp, a small ...
Dejiang Liu   +5 more
doaj   +1 more source

Age distribution and associated factors of cornea biomechanical parameter stress-strain index in Chinese healthy population

open access: yesBMC Ophthalmology, 2020
Background To investigate the new cornea biomechanical parameter stress-strain index (SSI) in Chinese healthy people and the factors associated with SSI. Methods A total of 175 eyes from 175 participants were included in this study.
Guihua Liu   +7 more
doaj   +1 more source

A combination of CMC and α-MSH inhibited ROS activated NLRP3 inflammasome in hyperosmolarity stressed HCECs and scopolamine-induced dry eye rats

open access: yesScientific Reports, 2021
An important mechanism involved in dry eye (DE) is the association between tear hyperosmolarity and inflammation severity. Inflammation in DE might be mediated by the NLRP3 inflammasome, which activated by exposure to reactive oxygen species (ROS).
Ying Lv   +8 more
doaj   +1 more source

A systematic analysis of marine lysogens and proviruses

open access: yesNature Communications, 2023
Viruses are ubiquitous in the oceans, exhibiting high abundance and diversity. Here, we systematically analyze existing genomic sequences of marine prokaryotes to compile a Marine Prokaryotic Genome Dataset (MPGD, consisting of over 12,000 bacterial and ...
Yi Yi   +14 more
doaj   +1 more source

In utero Exposure to Excessive Estrogen Impairs Homologous Recombination and Oogenesis via Estrogen Receptor 2 in Mice

open access: yesFrontiers in Cell and Developmental Biology, 2021
The association between the accumulation of synthetic chemicals with estrogenic activity and risks to oogenesis has become a growing concern. This study indicates that in utero estrogen exposure can affect homologous recombination in early oogenesis and ...
Xinyi Mu   +19 more
doaj   +1 more source

Seepage Behaviour of Fractured Rock Mass Infilling Using Different Transfixion Rates under Cyclic Loading

open access: yesGeofluids, 2021
It is very important to determine the seepage behaviour of fractured rock mass infilling to evaluate the stability of the surrounding rock. The joint transfixion rate is the ratio of the unpenetrated length to the penetration length of a joint in a ...
Shuren Wang   +3 more
doaj   +1 more source

Controlling Vibration Speed in Tunnel Excavation Using Fine Blasting Method under Complex Environmental Conditions

open access: yesShock and Vibration, 2021
It is very important to reduce the impact of blasting vibration on the surrounding structures during the tunnel drilling-blasting excavation. Taking the diversion tunnel of the urban water supply project in Zhumadian, Henan Province, China, as an example,
Yingcai Zhang   +3 more
doaj   +1 more source

Comparison between two autorefractor performances in large scale vision screening in Chinese school age children [PDF]

open access: yesInternational Journal of Ophthalmology, 2020
AIM: To evaluate the effectiveness of Grand Seiko Ref/Keratometer WAM-5500 compared to Topcon KR800 autorefractor in detecting refractive error in large scale vision screening for Chinese school age children with the WHO criteria.
Di Wang   +8 more
doaj   +1 more source

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