Results 31 to 40 of about 185,317 (276)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Lorsque le contrôle des migrations prend le pas sur la sauvegarde de la vie en mer : l’émergence des frontières dans la zone de responsabilité SAR espagnole

Criminologie
Selon les conventions internationales régissant le sauvetage en mer, les frontières maritimes ne doivent pas interférer avec les opérations de sauvetage en mer, la sauvegarde de la vie en mer étant définie comme prioritaire. Pourtant, depuis 2015 et dans
Arnaud Banos, Luna Vives, Camille Martel, Elizabeth Hessek, Kira Williams   +4 more
doaj   +1 more source

OANTA, G.A. and SÁNCHEZ RAMOS, B. (eds.), Irregular Migrations in Europe: A Perspective from the Sea Basins, Editoriale Scientifica, Naples, 2022, 362 pages

Paix et Sécurité Internationales, 2023
Schreinmoser, C. R. (2023). OANTA, G.A. and SÁNCHEZ RAMOS, B. (eds.), Irregular Migrations in Europe: A Perspective from the Sea Basins, Editoriale Scientifica, Naples, 2022, 362 pages. PEACE & SECURITY-PAIX ET SÉCURITÉ INTERNATIONALES (EuroMediterranean
Christoph R. Schreinmoser
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Equilibri e squilibri demografici tra Bacino Mediteraneo, Unione Europea e Mondo Arabo [PDF]

Polis: Revista de Stiinte Politice, 2014
With this research paper the authors do a pertinent analysis of the demographic balances and imbalances and their influence on the international migration phenomenon, in regards to the Mediterranean Basin, the European Union and the Arab world. Starting
Luigi Di COMITE, Simona GIORDANO
doaj  

Religion and international migration

, 2021
This is a draft chapter/article. The final version is available in Kaya, Ayhan (2021). “Religion and International migration," In Jeffrey Haynes (ed.), Handbook on Religion and International Relations. Cheltenham: Edward Elgar: 156-170. The material cannot be used for any other purpose without further permission of the publisher, and is for private ...
openaire   +2 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Au Sahel central : invisibilité d’un régime migratoire intra-africain ?

Revue Européenne des Migrations Internationales
Having remained on the sidelines of research on international migrations, the central Sahel is nevertheless characterized by longstanding intra-African and circular movements.
Florence Boyer
doaj   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Les étudiants polonais réfugiés en France (1830-1945), sources et pistes de recherche

Les Cahiers de Framespa, 2010
This paper is methodological with the aim in view to present ways of research and available archives about Polish students in France during the XIXth century, until 1945.
Caroline Barrera
doaj   +1 more source