Results 61 to 70 of about 653,218 (266)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
CONVERGENCE OF INTERNATIONAL AUDIT STANDARDS AND AMERICAN AUDIT STANDARDS REGARDING SAMPLING [PDF]
Annals of the University of Oradea: Economic Science, 2013 : Sampling is widely used in market research, scientific analysis, market analysis, opinion polls and not least in the financial statement audit. We wonder what is actually sampling and how did it appear?
Chis Anca Oana, Danescu Tatiana, ,
doaj
Uncertainty evaluation of the determination of benzo (α) pyrene in edible oils
Liang you shipin ke-ji, 2019 Benzo (α) pyrene in soybean oil was determined by molecular imprinting column purification combined with high performance liquid chromatography (MIC-HPLC).The whole process was analyzed to evaluate the uncertainty of the analytical results.Meanwhile, the
LI Xue +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Developing Clinical Nursing Education Standards in Iran Based on International Standards [PDF]
مجله ایرانی آموزش در علوم پزشکی, 2010 Introduction: Accreditation is one of the most important quality assurance and improvement methods in medical sciences education, especially in the field of nursing clinical education.
Nayereh Naseri +3 more
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A Future History of International Blockchain Standards
The Journal of The British Blockchain Association, 2018 Blockchain and blockchain-related technologies are being rapidly invented to the point that it is difficult to define specifically which properties are necessary to constitute a blockchain.
David Hyland-Wood +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Selçuk Üniversitesi Sosyal Bilimler Meslek Yüksekokulu Dergisi, 2019 The growing population of elderly and disabled people not only in Europe but also all over the world needs a special support and service, developed the new emerging new niche as an accessible tourism in tourism industry. Accessible tourism enables people
Metr Sezgin, SEYDA Sarı, Mahmut Ciderol
doaj +1 more source