Results 51 to 60 of about 2,308,410 (255)

New Deterrence in the new Order and Structure of the International System(Theoretical Data and Empirical Findings) [PDF]

open access: yesعلوم و فنون نظامی, 2017
Deterrence as one the most important areas of study in international relations and strategic studies, is included in scientific issues that is raised as the most important subject of strategic studies.
mehdi esfandyari   +2 more
doaj  

EVALUATION OF THE INTERNATIONAL SYSTEM IN RUSSIAN OFFICIAL DISCOURSE AND ACADEMIC ANALYSIS

open access: yesVestnik MGIMO-Universiteta, 2016
The article draws a comparison between Russian official and expert foreign policy discourses, focusing on representations of the power balance and relations between major states as the defining features of international system.
I. A. Istomin
doaj   +1 more source

Multilateralism and Nationalism in an Era of Disruption: the Great Pandemic and International Politics

open access: yesМеждународная аналитика, 2020
The Great Pandemic of 2020 has caused a shock to international politics. But has it forced a radical restructuring of the international system and a change in the way international actors behave?
R. Sakwa
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

The U.S. Imperial Jugger-not: Saturation Points and Cultural Globalization [PDF]

open access: yesIntegral Review, 2010
Globalization is not merely inevitable western cultural conquest. The assumption that the juggernaut of western hegemonic domination will continue until the world is consumed is a common one, but not an accurate one.
Meg Spohn Bertoni
doaj  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

The Competition of Dominant Powers in the International System and the US-China Encounter in the Horn of Africa (2012-2022)

open access: yesGüvenlik Stratejileri Dergisi
This study examines the power competition between the United States (US) and China in the Horn of Africa within the framework of Power Transition Theory (PTT). Using the concept of dissatisfaction, the study explores three main hypotheses: 1) the US as a
Kaan Devecioğlu
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

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