Results 21 to 30 of about 112,975 (261)

Antioxidant and a-amylase Inhibitory Activities and Phytocompounds of Clausena indica Fruits

Medicines, 2020
Background: Clausena indica fruit is commonly used for food ingredients and traditional medicines in tropical countries, however, information about its biological activities and chemical profiles has been inadequately reported.
La Hoang Anh, Tran Dang Xuan, Nguyen Thi Dieu Thuy, Nguyen Van Quan, Le Thu Trang   +4 more
doaj   +1 more source

Tendencies in the Development of International Scientific and Technological Cooperation [PDF]

Business Inform, 2020
In recent decades, there has been an intensification of international scientific and technological cooperation (ISTC), which takes place in various forms. The publication is aimed at generalizing the methodological bases of research and examining the main tendencies in the development of modern ISTC.
M. V. Polyakov, V. S. Bilozubenko, S. Y. Shablii   +2 more
openaire   +2 more sources

Design and implementation of the wheel-clamping stay cable inspection robot

Advances in Mechanical Engineering, 2023
A new wheel-clamping type inspection robot for bridge stay cables was designed. Its clamping mechanism adopts a four-auxiliary-two-drive wheel clamping scheme, and the driving unit utilizes a single motor with double output shaft.
Yongming Wang, Xiang Li, Mingxing Yang, Feng Yin   +3 more
doaj   +1 more source

PM2.5 increases mouse blood pressure by activating toll-like receptor 3

Ecotoxicology and Environmental Safety, 2022
Background and aims: Plenty of literature has documented that fine particulate matter (PM2.5) exposure is related to blood pressure (BP) elevation. Vascular dysfunction is the initiation of cardiovascular diseases, such as hypertension.
Jinna Zhang, Rucheng Chen, Guoqing Zhang, Yixuan Wang, Jing Peng, Renjie Hu, Ran Li, Weijia Gu, Lu Zhang, Qinghua Sun, Cuiqing Liu   +10 more
doaj   +1 more source

International activity of the innovative enterprises – experience and recommendations [PDF]

Eastern European Journal of Regional Studies, 2018
Research background: In the international literature we can find great examples of research in the field of innovation and technological cooperation boosting between companies.
Zofia GRÓDEK-SZOSTAK, Karolina KOTULEWICZ-WISIŃSKA, Małgorzata LUC   +2 more
doaj  

F7 and topotecan co-loaded thermosensitive liposome as a nano-drug delivery system for tumor hyperthermia

Drug Delivery, 2020
In order to enhance the targeting efficiency and reduce anti-tumor drug’s side effects, topotecan (TPT) and F7 were co-loaded in thermosensitive liposomes (F7-TPT-TSL), which show enhanced permeability and retention in tumors, as well as local controlled
Chunyang Du, Shuangshuang Li, Yuan Li, Hervé Galons, Na Guo, Yuou Teng, Yongmin Zhang, Mingyuan Li, Peng Yu   +8 more
doaj   +1 more source

Identification and Functional Verification of Cold Tolerance Genes in Spring Maize Seedlings Based on a Genome-Wide Association Study and Quantitative Trait Locus Mapping

Frontiers in Plant Science, 2021
Maize (Zea mays L.) is a tropical crop, and low temperature has become one of the main abiotic stresses for maize growth and development, affecting many maize growth processes.
Yukun Jin, Zhongren Zhang, Yongjing Xi, Zhou Yang, Zhifeng Xiao, Shuyan Guan, Jing Qu, Piwu Wang, Rengui Zhao   +8 more
doaj   +1 more source

Liver protects neuron viability and electrocortical activity in post-cardiac arrest brain injury

EMBO Molecular Medicine
Brain injury is the leading cause of mortality among patients who survive cardiac arrest (CA). Clinical studies have shown that the presence of post-CA hypoxic hepatitis or pre-CA liver disease is associated with increased mortality and inferior ...
Zhiyong Guo, Meixian Yin, Chengjun Sun, Guixing Xu, Tielong Wang, Zehua Jia, Zhiheng Zhang, Caihui Zhu, Donghua Zheng, Linhe Wang, Shanzhou Huang, Di Liu, Yixi Zhang, Rongxing Xie, Ningxin Gao, Liqiang Zhan, Shujiao He, Yifan Zhu, Yuexin Li, Björn Nashan, Schlegel Andrea, Jin Xu, Qiang Zhao, Xiaoshun He   +23 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source