Results 71 to 80 of about 13,408 (279)

The Burden and Coping Mechanisms among the Caregivers of Immobilized Elderly Patients: A Multinational Comparative Study

open access: yesIranian Journal of Nursing and Midwifery Research
Background: Caregivers face various difficulties that put a huge burden on them, especially when dealing with immobilized elderly patients. This study aimed to compare caregivers’ burdens and coping mechanisms during the care of immobilized elderly ...
Sameer H. Hafez   +5 more
doaj   +1 more source

Between a White Cube, Black Box, and Warehouse: Constructing Spaces for Contemporary Art throughout the Recent Museum Building Boom [PDF]

open access: yes, 2018
Since the 1990s, museum buildings and the art housed inside them have undergone dramatic changes. Once canonical structures, they have evolved to more suitably contain new art forms and reflect the expanding and dynamic purposes of the museum.
Murphy, Diana K.
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Internationalisierung der Translationswissenschaft? : zum Aktualitätsdefizit der De-Westernizing-Debatte

open access: yesBrünner Beiträge zur Germanistik und Nordistik, 2018
Under the banner of the international turn and De-Westernization, a lively discussion of fundamental questions has been taking place in recent years.
Lavinia Heller
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Concept “Legally Constituted Court” of National and International Law (Definition Problem)

open access: yesУправленческое консультирование, 2018
The article analyzes the interpretation of the category «out established by law» in national and international law, as well as in the practice of international law enforcement agencies.
Inna Anatolyevna Orlova
doaj   +1 more source

Internacionalidad de revistas académicas: Un estudio de caso con RELIE-VE [PDF]

open access: yes, 2007
Se revisa elconcepto y los criterios propuestos en la literatura para establecer que unarevista es 'internacional'. Se aplican posteriormente estos criterios alanálisis de las características de RELIEVE (la Revista ELectrónica de Investigación y ...
Aliaga Abad, F.   +1 more
core  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Pathways from trade to health

open access: yesRevista Panamericana de Salud Pública, 2018
International trade has increased over time, both in volume and as a share of gross domestic product, and international trade agreements have proliferated. This rise in trade has many potential impacts on health outcomes.
Teresa Cyrus
doaj   +1 more source

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