Results 51 to 60 of about 887,471 (296)

Internet-based psychoeducation for bipolar disorder: a qualitative analysis of feasibility, acceptability and impact [PDF]

, 2012
<p>Background: In a recent exploratory randomised trial we found that a novel, internet-based psychoeducation programme for bipolar disorder (Beating Bipolar) was relatively easy to deliver and had a modest effect on psychological quality of life ...
A Darzi, A Steckler, AJ Winzelberg, Colom and Vieta, D Castle, Daniel J Smith, Department of Health, DJ Smith, DJ Smith, E Barnes, E Vieta, F Colom, F Colom, F Eker, GE Simon, H Atherton, J Green, J Nicholas, J Ritchie, M Bauer, MS Bauer, MS Bauer, Office of National Statistics, P Klemm, Ria Poole, SAH Gerhards, Sharon A Simpson, V Braun, Y Setoyama   +28 more
core   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

A randomized controlled trial of an Internet-based intervention for eating disorders and the added value of expert-patient support: study protocol

Trials, 2019
Background E-mental health has become increasingly popular in interventions for individuals with eating disorders (EDs). It has the potential to offer low-threshold interventions and guide individuals to the needed care more promptly. Featback is such an
Pieter J. Rohrbach, Alexandra E. Dingemans, Philip Spinhoven, Elske Van den Akker-Van Marle, Joost R. Van Ginkel, Marjolein Fokkema, Markus Moessner, Stephanie Bauer, Eric F. Van Furth   +8 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A systematic review of internet-based worksite wellness approaches for cardiovascular disease risk management: outcomes, challenges & opportunities. [PDF]

, 2014
ContextThe internet is gaining popularity as a means of delivering employee-based cardiovascular (CV) wellness interventions though little is known about the cardiovascular health outcomes of these programs.
Agatston, Arthur S, Al-Mallah, Mouaz H, Aneni, Ehimen C, Blaha, Michael J, Blankstein, Ron, Blumenthal, Roger S, Budoff, Matthew J, Feldman, Theodore, Maziak, Wasim, Nasir, Khurram, Roberson, Lara L, Rouseff, Maribeth, Tran, Thinh H   +12 more
core  

Internet-based cognitive behavioural therapy for subthreshold depression in people over 50 years old:a randomized controlled clinical trial [PDF]

, 2007
Background. Subthreshold depression is a highly prevalent condition and a risk factor for developing a major depressive episode. Internet-based cognitive behaviour therapy may be a promising approach for the treatment of subthreshold depression.
Allison, Cohen, Cole, Haringsma, HELEEN RIPER, IVAN NYKLÍČEK, JULES KEYZER, Lewinsohn, NIELS SMITS, PIM CUIJPERS, Van der Does, VICTOR POP, VIOLA SPEK   +12 more
core   +3 more sources

Effect of Tailoring in an Internet-Based Intervention for Smoking Cessation: Randomized Controlled Trial

Journal of Medical Internet Research, 2011
BackgroundStudies suggest that tailored materials are superior to nontailored materials in supporting health behavioral change. Several trials on tailored Internet-based interventions for smoking cessation have shown good effects.
Wangberg, Silje C, Nilsen, Olav, Antypas, Konstantinos, Gram, Inger Torhild   +3 more
doaj   +1 more source

Effects of internet-based, psychosocial, and early medical interventions on professional burnout in health care workers: Systematic literature review and meta-analysis

Internet Interventions, 2023
Background: The prevalence of professional burnout increased among healthcare workers during the coronavirus 2019 (COVID-19) pandemic, with negative effects on their mental health.
Mayra Daniela Maldonado Ladino, Cristina Bolaños, Viviana Andrea Calderón Ramírez, Edward John Silva Giraldo, Juan Pablo Álzate, Angela Cubides, Alejandro Botero Carvajal   +6 more
doaj   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Internet-based brief intervention for young men with unhealthy alcohol use: a randomized controlled trial in a general population sample. [PDF]

, 2015
To test the efficacy of an internet-based brief intervention (IBI) in decreasing alcohol use among young Swiss men aged 21 years on average. Two parallel-group randomized controlled trial with a 1 : 1 allocation ratio containing follow-up assessments at ...
Bertholet, N., Burnand, B., Cunningham, J.A., Daeppen, J.B., Faouzi, M., Gaume, J., Gmel, G.   +6 more
core   +1 more source