Results 131 to 140 of about 2,371,895 (313)

NanoBERTa-ASP: predicting nanobody paratope based on a pretrained RoBERTa model

open access: yesBMC Bioinformatics
Background Nanobodies, also known as VHH or single-domain antibodies, are unique antibody fragments derived solely from heavy chains. They offer advantages of small molecules and conventional antibodies, making them promising therapeutics.
Shangru Li   +4 more
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

ICT Kids Online Brazil: Survey on Internet Use by Children in Brazil (TIC KIDS ONLINE BRASIL Pesquisa sobre o Uso da Internet por Crianças e Adolescentes no Brasil) [PDF]

open access: yes, 2020
The goal of the ICT Kids Online survey is to generate evidence about the opportunities and risks associated with Internet use among individuals 9 to 17 years old in Brazil.
Brazilian Internet Steering Committe (Comitê Gestor da Internet no Brasil)
core   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi   +17 more
wiley   +1 more source

Commercial Data Privacy and Innovation in the Internet Economy: A Dynamic Policy Framework

open access: yesThe Journal of Privacy and Confidentiality, 2011
Department of Commerce Internet Policy Task Force
doaj   +1 more source

Internet of Things to Internet of Humans: A Perception

open access: yesHuman-Centric Intelligent Systems
Abstract The use of internet has grown significantly in the last three decades. Various technologies such as social media and networking, cloud systems, Blockchain technology etc., have been developed which have significantly improved the communication between the humans across the globe; and also, between the devices which has led to the ...
Ghazanfar Ali Safdar   +2 more
openaire   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin   +8 more
wiley   +1 more source

Economics of Internet interdomain interconnections [PDF]

open access: yes, 2015
Aquesta tesi estudia els aspectes econòmics de la interconnexió entre Ases, identifica desafiaments que amenacen el futur d'Internet i proposa solucions per resoldre'ls. Primerament vam realitzar el primer estudi analític i empíric sobre el peering remot,
De Castro Arribas, Ignacio   +1 more
core  

A Medium- and Long-Term Residential Load Forecasting Method Based on Discrete Cosine Transform-FEDformer

open access: yesEnergies
Accurate and reliable medium- and long-term load forecasting is crucial for the rational planning and operation of power systems. However, existing methods often struggle to accurately extract and capture long-term dependencies in load data, leading to ...
Dengao Li   +3 more
doaj   +1 more source

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