Results 41 to 50 of about 6,954,768 (336)

Survey of intrusion detection systems: techniques, datasets and challenges

Cybersecurity, 2019
Cyber-attacks are becoming more sophisticated and thereby presenting increasing challenges in accurately detecting intrusions. Failure to prevent the intrusions could degrade the credibility of security services, e.g. data confidentiality, integrity, and
Ansam Khraisat, Iqbal Gondal, Peter Vamplew, Joarder Kamruzzaman   +3 more
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Computational Soundness for Dalvik Bytecode

, 2016
Automatically analyzing information flow within Android applications that rely on cryptographic operations with their computational security guarantees imposes formidable challenges that existing approaches for understanding an app's behavior struggle to
Backes M., Backes M., Barthe G., Galindo D., Internet, Lochbihler A., Shao J.   +6 more
core   +1 more source

Reduced-Reference Stereoscopic Image Quality Assessment Using Gradient Sparse Representation and Structural Degradation

IEEE Access, 2021
Reduced-reference stereoscopic image quality assessment (RRSIQA) models evaluate stereoscopic image quality degradation with partial information about the “ideal-quality” reference stereopair.
Jian Ma, Guoming Xu, Xiyu Han
doaj   +1 more source

Guide to the Internet: Introducing the Internet [PDF]

BMJ, 1995
The benefits to medical practitioners of using the Internet are growing rapidly as the Internet becomes easier to use and ever more biomedical resources become available on line. The Internet is the largest computer network in the world; it is also a virtual community, larger than many nation states, with its own rules of behaviour or "netiquette ...
openaire   +3 more sources

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Improved Pedestrian Dead Reckoning Based on a Robust Adaptive Kalman Filter for Indoor Inertial Location System

Sensors, 2019
Pedestrian dead reckoning (PDR) systems based on a microelectromechanical-inertial measurement unit (MEMS-IMU) providing advantages of full autonomy and strong anti-jamming performance are becoming a feasible choice for pedestrian indoor positioning.
Qigao Fan, Hai Zhang, Peng Pan, Xiangpeng Zhuang, Jie Jia, Pengsong Zhang, Zhengqing Zhao, Gaowen Zhu, Yuanyuan Tang   +8 more
doaj   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

MetricSifter: Feature Reduction of Multivariate Time Series Data for Efficient Fault Localization in Cloud Applications

IEEE Access
Automated fault localization in large-scale cloud-based applications is challenging because it involves mining multivariate time series data from large volumes of operational monitoring metrics.
Yuuki Tsubouchi, Hirofumi Tsuruta
doaj   +1 more source