Results 41 to 50 of about 2,367,787 (313)
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
IEEE AccessAutomated fault localization in large-scale cloud-based applications is challenging because it involves mining multivariate time series data from large volumes of operational monitoring metrics.
Yuuki Tsubouchi, Hirofumi Tsuruta
doaj +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Rapid rise and decay in petition signing
EPJ Data Science, 2017 Contemporary collective action, much of which involves social media and other Internet-based platforms, leaves a digital imprint which may be harvested to better understand the dynamics of mobilization. Petition signing is an example of collective action
Taha Yasseri +2 more
doaj +1 more source
Spider Mites Detection in Wheat Field Based on an Improved RetinaNet
Agriculture, 2022 As a daily staple food of more than one third of the world’s population, wheat is one of the main food crops in the world. The increase in wheat production will help meet the current global food security needs.
Denghao Pang +3 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
, 2023 copyright UK Data Service and data collection copyright owner.The Oxford Internet Surveys (OxIS) is the longest-running academic survey of internet use in Britain, describing how internet use has evolved from 2003 to the present day.
University of Oxford, Oxford Internet Institute
core +2 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
, 2023 copyright UK Data Service and data collection copyright owner.The Oxford Internet Surveys (OxIS) is the longest-running academic survey of internet use in Britain, describing how internet use has evolved from 2003 to the present day.
University of Oxford, Oxford Internet Institute
core +2 more sources