Results 71 to 80 of about 7,151,756 (306)

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Perceived value of video games, but not hours played, predicts mental well-being in casual adult Nintendo players

Royal Society Open Science
Studies on video games and well-being often rely on self-report measures or data from a single game. Here, we study how 703 casually engaged US adults’ time spent playing for over 140 000 h across 150 Nintendo Switch games relates to their life ...
Nick Ballou, Matti Vuorre, Thomas Hakman, Kristoffer Magnusson, Andrew K. Przybylski   +4 more
doaj   +1 more source

Taking advantage of motif matrix inference for rotated image indexing and retrieval

EURASIP Journal on Advances in Signal Processing, 2018
With the rapid development of information technology, the sizes of digital libraries become larger and larger. How to quickly and effectively search the desired images in huge digital libraries becomes the challenge needed to resolve with high priority ...
Yi Xu, Wei Song, Yu Yan, Huadong Zhu, Ting Cao   +4 more
doaj   +1 more source

Understanding the Internet: Psychological word norms as indicators of query-specific internet word frequencies [PDF]

, 2008
By using existing psychological word norms obtained by rating procedures we try to predict the frequencies of search hits derived from internet search engines.
Heine, Jörg-Henrik, Spörrle, Matthias
core   +1 more source

Internet pharmacies [PDF]

International Psychiatry, 2006
Shopping on the internet has become routine for many people and covers a wide range of products and services. It is therefore unsurprising that, in some countries, medical and pharmaceutical services can also be bought. This has clear advantages in countries such as Australia, where some communities are isolated by huge distances (or other geographical
openaire   +2 more sources

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

An Algorithm of Factor Graph Optimization for 3D Map of Unmanned Exploration Vehicle in Tunnel Environment

Journal of Robotics
The simultaneous localization and mapping (SLAM) technology based on LiDAR has not only achieved real-time localization of unmanned exploration vehicles in unknown environments but also efficiently obtained three-dimensional geospatial information of the
Jian Xie, Rao Li, Jing Li, Aoshu Xu
doaj   +1 more source

Toward a social compact for digital privacy and security [PDF]

Executive summary The Global Commission on Internet Governance (GCIG) was established in January 2014 to articulate and advance a strategic vision for the future of Internet governance. In recent deliberations, the Commission discussed the potential for
Global Commission on Internet Governance
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