Results 131 to 140 of about 7,984,874 (287)

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

Advanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang, Zhicheng Zhou, Xue Jiang, Zhenguang Du, Yangyang Zhan, Xinli Liu   +5 more
wiley   +1 more source

Social media capital, facilitating conditions, and digital self-efficacy: an integrated model of internet entrepreneurship intention in India

Cogent Education
Advancements in digital technology have lowered barriers to student entrepreneurship by reducing startup costs and infrastructure needs, making internet entrepreneurship a viable option for aspiring entrepreneurs in emerging economies.
Regina Babu Kivuyo, Renjini Das, Khadija Swalehe Mbarak   +2 more
doaj   +1 more source

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

Advanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian, Qianyu Wang, Wenyan Gao, Xianfeng Li, Jiawen Fan, Xiaoliang Wu, Siqi Liu, Xiangdong Ming, Danna Yeerken, Mutian Shen, Qingjie Min, Qimin Zhan, Yan Wang   +12 more
wiley   +1 more source

Internet Self-Efficacy and the Use of Electronic Information Services Acceptance

International Journal of Information Science and Management, 2019
Self-efficacy and the use of electronic information services acceptance among the university students can affect the learners' online services. This is the due to the learners' acceptance of using technology and its role in their life.
Neda Zarei, Fariba Nazari, Mohammad Reza FarhadPoor   +2 more
doaj  

Internet exposure and knowledge of HIV/AIDS among adolescents in India: exploring the mediating role of self-efficacy using UDAYA data

Frontiers in Communication
IntroductionIn culturally conservative environments, adolescents are more likely to seek sexual health information from the internet, where traditional channels of communication are hindered.
Sridhar Prinitha, Tony P. Jose
doaj   +1 more source

A STUDY OF SINGAPORE FEMALE PRIMARY TEACHERS’ SELF-EFFICACY FOR TEACHING SCIENCE [PDF]

, 2011
According to Bandura, self-efficacy is defined as an individual’s judgment of their capability to organize and execute the courses of action required to attain designated types of performances.
NG, WEE-LOON
core  

Discovery and Optimization of AMT‐676, a CDH17‐Targeting ADC for the Treatment of Advanced Gastrointestinal Cancers

Advanced Science, EarlyView.
AMT‐676 is a novel antibody‐drug conjugate targeting CDH17, an adhesion molecule uniquely exposed on gastrointestinal tumor surfaces. Engineered with an optimized exatecan payload, it demonstrates profound tumor regression and a robust bystander effect across diverse preclinical models.
Ying‐nan Wang, Dan‐yun Ruan, Jing Shi, Yue Huang, Hui Sheng, Ya‐ling Huang, Linjie Ma, Lijun Wang, Caiwei Chen, Yixuan Wang, Yue Zhang, Yi Shen, Qing Zhang, Jianjian Zhang, Yanfang Tang, Jin‐ling Zhang, Jia‐jia Hu, Chen‐yi Wu, Jia‐ying Chen, Xun Meng, Shu‐Hui Liu, Feng Wang   +21 more
wiley   +1 more source

Evaluating a brief self-affirmation intervention to increase college students’ intentions to reduce internet use: A randomized controlled trial

Computers in Human Behavior Reports
Background: Internet overuse among youth is a significant health problem. Although self-affirmation interventions combined with health risk information have shown promise in addressing unhealthy behaviors, their application to problematic Internet use ...
Rui She, Aobo Liu, Haiyue Luo, Lu Ma
doaj   +1 more source

Near‐Infrared Fluorescent PROTAC Enables Theranostic Imaging and Selective Tau Degradation in Alzheimer's Disease

Advanced Science, EarlyView.
Here, we report a novel NIR fluorescent PROTAC platform that enables real‐time imaging and targeted degradation of Alzheimer's p‐Tau. Our lead compound effectively clears p‐Tau, reduces APP/Aβ, and alleviates cognitive deficits in AD mice. This work demonstrates a theranostic strategy for visualizing degradation and developing next‐generation AD ...
Ziwei Ren, Qian Yue, Ning Gao, Qiu‐Lian Hao, Yan Huo, Chuchu Li, Xinyue Leng, Lu‐Lu Sun, Maggie Pui Man Hoi, Hai‐Hao Han, Mingliang Ma, Xu‐Wen Li   +11 more
wiley   +1 more source

Social support, computer self-efficacy, online learning engagement and satisfaction among undergraduate hospitality students

Cogent Education
Following the outbreak of COVID-19, the adoption of online teaching and learning in universities has witnessed phenomenal growth. Importantly, online learning engagement and satisfaction have consequences on student learning outcomes and behavioural ...
Christopher Mensah, Mawufemor A. Kugbonu, Melody E. Appietu, Gifty A. Nti, Mavis Adjoa Forson   +4 more
doaj   +1 more source