Results 41 to 50 of about 175,343 (264)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Competitive Intelligence and Internet Sources [PDF]

open access: yesInformatică economică, 2007
In the Knowledge Age to maintain profitability and in some cases to remain in the market, companies must focus their actions in activities such as collecting, filtering, and disseminating information about market, about competitors and their actions ...
doaj  

Problems ofrealization right tofreedom of speech in information internet-sources

open access: yesПроблеми Законності, 2018
The article is considered meaning of grounds and realization freedom of speech inthe Internet. The author studies issue of guarantees of the right to freedom of expression in online-information sources in the context of democratic state.
Тетяна Миколаївна Слінько   +1 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

USING INTERNET SOURCES IN TEACHING ECONOMIC SUBJECTS

open access: yesВысшее образование в России, 2016
This paper examines the possibility of increasing the efficiency of the learning process by using economic and scientific information sources. The authors demonstrate that for improving the quality of higher education it is necessary to use Internet ...
Svetlana V. Kulikova   +1 more
doaj  

Educational behaviors of pregnant women in the Bronx during Zika’s International emerging epidemic: “First mom … and then I’d Google. And then my doctor”

open access: yesBMC Pregnancy and Childbirth, 2021
Background The objective of the study was to understand how pregnant women learned about Zika infection and to identify what sources of information were likely to influence them during their pregnancy.
Miguel Rodriguez   +3 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Trends and Prospects in Venture and Angel Investments in New Media Companies

open access: yesPrometheus, 2001
How do 'new media' or Internet-related companies raise external equity capital? In this paper, I analyze two markets that entrepreneurs of private Internet-related businesses use in the US to raise equity: the venture capital market and the market for ...
Stephen Prowse
doaj   +1 more source

Comparing the pharmacology knowledge and performance of nurses and nursing students in the use of information resources in pediatrics wards: An observational study

open access: yesSAGE Open Medicine, 2022
Objectives: One of the major duties of nurses is proper medication administration while maintaining patient safety, which requires sufficient knowledge and practice.
Amir Shahzeydi   +6 more
doaj   +1 more source

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