Results 281 to 290 of about 458,579 (386)

Effects of Hepatic or Renal Impairment on Pharmacokinetics of Fruquintinib

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Fruquintinib (FRUZAQLATM) is a highly selective tyrosine kinase inhibitor of all three vascular endothelial growth factor receptors (‐1, ‐2, and ‐3). Two Phase 1, open‐label, single‐dose studies investigated the impact of hepatic or renal impairment on the pharmacokinetics and tolerability of fruquintinib.
Martha Gonzalez   +8 more
wiley   +1 more source

Assessment of the Effects of Fruquintinib on Cardiac Safety in Patients with Metastatic Colorectal Cancer

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Fruquintinib is a highly selective oral inhibitor of vascular endothelial growth factor receptors 1, 2, and 3, approved by the US Food and Drug Administration and the European Commission for the treatment of previously treated metastatic colorectal cancer (mCRC), regardless of biomarker status. This study used concentration QT interval (C‐QTc)
Xiaofei Zhou   +7 more
wiley   +1 more source

Abdominal POCUS Education for Clinicians: A Systematic Review of Teaching Methods for Point‐of‐Care Abdominal Ultrasonography

open access: yesJournal of Clinical Ultrasound, Volume 53, Issue 3, Page 547-561, March/April 2025.
For patients to benefit from abdominal point‐of‐care ultrasound, the ultrasound examinator must be sufficiently trained. In this systematic review, we identified advantages and disadvantages of different training methods and approaches. We conclude that thoughtful integration of the various educational methods is crucial for stakeholders and educators.
Birkir Örn Sveinsson   +5 more
wiley   +1 more source

Dissertation while on internship: Obstacles and predictors of progress.

open access: green, 2000
Thomas S. Krieshok   +3 more
openalex   +3 more sources

Development and Validation of a Teaching Module for Prescription Writing for Dental Students: A Randomized Controlled Trial

open access: yesJournal of Dental Education, EarlyView.
ABSTRACT Objectives Dentists commonly encounter patients with complex medical comorbidities that require an advanced level of competence in the art of prescription writing. However, the current structure of dental education often places limited emphasis on this critical skill.
Praveen Jodalli   +3 more
wiley   +1 more source

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