Results 31 to 40 of about 4,595 (149)

Stress Related Shift Toward Inflammaging in Cosmonauts After Long-Duration Space Flight

Frontiers in Physiology, 2019
Space flight exerts a specific conglomerate of stressors on humans that can modulate the immune system. The mechanism remains to be elucidated and the consequences for cosmonauts in the long term are unclear. Most of the current research stems from short-
Judith-Irina Buchheim, Sandra Matzel, Marina Rykova, Galina Vassilieva, Sergey Ponomarev, Igor Nichiporuk, Marion Hörl, Dominique Moser, Katharina Biere, Matthias Feuerecker, Gustav Schelling, Detlef Thieme, Ines Kaufmann, Ines Kaufmann, Manfred Thiel, Alexander Choukèr   +15 more
doaj   +1 more source

The magnitude and effects of extreme solar particle events

Journal of Space Weather and Space Climate, 2014
The solar energetic particle (SEP) radiation environment is an important consideration for spacecraft design, spacecraft mission planning and human spaceflight.
Jiggens Piers, Chavy-Macdonald Marc-Andre, Santin Giovanni, Menicucci Alessandra, Evans Hugh, Hilgers Alain   +5 more
doaj   +1 more source

Spaceflight induces changes in gene expression profiles linked to insulin and estrogen

Communications Biology
Organismal adaptations to spaceflight have been characterized at the molecular level in model organisms, including Drosophila and C. elegans. Here, we extend molecular work to energy metabolism and sex hormone signaling in mice and humans.
Begum Aydogan Mathyk, Marshall Tabetah, Rashid Karim, Victoria Zaksas, JangKeun Kim, R. I. Anu, Masafumi Muratani, Alexia Tasoula, Ruth Subhash Singh, Yen-Kai Chen, Eliah Overbey, Jiwoon Park, Henry Cope, Hossein Fazelinia, Davide Povero, Joseph Borg, Remi V. Klotz, Min Yu, Steven L. Young, Christopher E. Mason, Nathaniel Szewczyk, Riley M. St Clair, Fathi Karouia, Afshin Beheshti   +23 more
doaj   +1 more source

Microbiota-Induced Radioprotection: A Novel Approach to Enhance Human Radioresistance with In-Situ Genetically Engineered Gut Bacteria

Applied Microbiology
The high sensitivity of living organic forms to space radiation remains the critical issue during spaceflight, to which they will be chronically exposed during months of interplanetary or even decades of interstellar spaceflight.
Anna O. Yakimova, Anastasiia Nikolaeva, Olesya Galanova, Victoria A. Shestakova, Ekaterina I. Smirnova, Alina Levushkina, Denis S. Baranovskii, Anna N. Smirnova, Vasiliy N. Stepanenko, Dmitry A. Kudlay, Peter V. Shegay, Andrey D. Kaprin, Dmitry V. Sosin, Ilya D. Klabukov   +13 more
doaj   +1 more source

Women in space: A review of known physiological adaptations and health perspectives

Experimental Physiology, EarlyView.
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford, Danielle J. Carroll, Heather C. M. Allaway, Bonnie J. Dunbar, Aenor J. Sawyer   +4 more
wiley   +1 more source

Confined spaces in space: Cerebral implications of chronic elevations of inspired carbon dioxide and implications for long‐duration space travel

Experimental Physiology, EarlyView.
Abstract Cerebrovascular regulation is critically dependent upon the arterial partial pressure of carbon dioxide (PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_{\mathrm{2}}}}}$), owing to its effect on cerebral blood flow, tissue PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_{\mathrm{2}}}}}$, tissue proton concentration, cerebral metabolism and cognitive and neuronal ...
Jay M. J. R. Carr, Philip N. Ainslie, Trevor Day   +2 more
wiley   +1 more source

Effects and Solutions on the Human Body After Long-Duration Space Flights [PDF]

, 2019
During the Cold War, President John F. Kennedy made it a mission for the National Aeronautics and Space Administration (NASA) to accomplish a lunar landing and return to Earth.
Esquivel Patricio, Jose Jaime
core   +1 more source

Current methodological approaches assessing the healthrelated risks assessment in manned spaceflight missions

Informaciâ i Innovacii
Further development of manned space exploration requires appropriate scientific and appropriate modern methodological approaches assessing the health risks of participants in missions to an orbital station with high inclination of the orbit and ...
A. V. Lobanov, E. D. Makeeva, D. O. Meshkov, S. A. Ponomarev, S. N. Cherkasov, A. F. Pashchenko, Yu. V. Sidelnikov   +6 more
doaj   +1 more source

The search for the ultimate exercise countermeasure to preserve crew health and ensure mission success in long‐duration spaceflight

Experimental Physiology, EarlyView.
Abstract The current understanding of crew health maintenance is founded upon decades of physiological research conducted in terrestrial spaceflight analogues and in low Earth orbit, particularly on the International Space Station. However, as we progress towards the Lunar Gateway and interplanetary missions, it is imperative that the tools employed to
Rodrigo Fernandez‐Gonzalo, Stefan Schneider, Martina Heer, Anna‐Maria Liphardt   +3 more
wiley   +1 more source

Analytical sun synchronous low-thrust manoeuvres [PDF]

, 2012
Article describes analytical sun synchronous low-thrust ...
Becerra V. M., Betts J. T., Betts J. T., Brown D. W., Hanson J. N., Malcolm Macdonald, McInnes C. R., Ramler J. R., Stephanie Y. Docherty, Vallado D., Wakker K. E.   +10 more
core   +1 more source