Results 161 to 170 of about 12,185 (226)

Snapshots of Motion: A Novel Structural Intermediate Reveals Conserved Dynamics in Archaeal DNA Ligases

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT We present the first x‐ray crystallographic structural evidence of an archaeal DNA ligase showing the AMP covalent adduct together with further cofactor hydrolysis, capturing a transient intermediary in the first step of the ligation reaction, triggered by the pyrophosphate hydrolysis.
A. X. Quintana‐Armas   +3 more
wiley   +1 more source

Forecast verification using information and noise

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
Verification of weather forecasts is usually expressed in terms of total error metrics. This is useful for end users of the forecasts but does not allow evaluation of the intrinsic information content of the forecasts. To overcome this limitation, we propose a new total error decomposition into information and noise error measures, connect it to ...
Massimo Bonavita, Alan J. Geer
wiley   +1 more source

Moisture inversions in the central Arctic: Product assessment and long‐wave radiative effect

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
This study evaluates the integrated water vapour and the vertical distribution of water vapour of state‐of‐the‐art reanalyses, weather forecast models, and ground‐ and space‐based remote‐sensing products in the central Arctic. A particular focus lies on the representation of humidity inversions and the quantification of the long‐wave radiative effect ...
Andreas Walbröl   +6 more
wiley   +1 more source

A composite‐loss graph neural network for the multivariate post‐processing of ensemble weather forecasts

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
The dual graph neural network (dualGNN), trained with a composite loss combining the energy score (ES) and variogram score (VS), consistently outperformed models optimized solely for ES or the continuous ranked probability score in the multivariate setting, as well as empirical copula approaches.
Mária Lakatos
wiley   +1 more source

A new smoother method for treating different timescales in variational data assimilation for coupled systems

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
We propose a new method for treating different timescales in coupled variational data assimilation for atmosphere–ocean models. The approach involves a series of short‐window coupled assimilations (red arrows in the schematic) followed by a long‐window correction to the ocean fields (blue arrow).
Amos S. Lawless   +3 more
wiley   +1 more source

Large Deformation Diffeomorphic Metric Curve Mapping. [PDF]

open access: yesInt J Comput Vis, 2008
Glaunès J, Qiu A, Miller MI, Younes L.
europepmc   +1 more source

A structurally localized ensemble Kalman filtering approach

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
We derive an inherently localized ensemble Kalman filtering (EnKF) approach, avoiding the need for any auxiliary localization technique. The idea is to first use the variational Bayesian optimization to approximate the (continuous) state analysis probability density function (pdf) by a product of independent marginal pdfs corresponding to small ...
Boujemaa Ait‐El‐Fquih   +1 more
wiley   +1 more source

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