Results 41 to 50 of about 138,381 (273)

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Deep Fluids: A Generative Network for Parameterized Fluid Simulations

, 2018
This paper presents a novel generative model to synthesize fluid simulations from a set of reduced parameters. A convolutional neural network is trained on a collection of discrete, parameterizable fluid simulation velocity fields.
Azevedo, Vinicius C., Gross, Markus, Kim, Byungsoo, Kim, Theodore, Solenthaler, Barbara, Thuerey, Nils   +5 more
core   +1 more source

Neural BTF Compression and Interpolation

Computer graphics forum (Print), 2019
The Bidirectional Texture Function (BTF) is a data‐driven solution to render materials with complex appearance. A typical capture contains tens of thousands of images of a material sample under varying viewing and lighting conditions.
G. Rainer, Wenzel Jakob, A. Ghosh, Tim Weyrich   +3 more
semanticscholar   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Editorial: Special Issue on Analytical and Approximate Solutions for Numerical Problems

Walailak Journal of Science and Technology, 2014
Though methods and algorithms in numerical analysis are not new, they have become increasingly popular with the development of high speed computing capabilities.
Walailak Journal of Science and Technology
doaj   +1 more source

Texture Mixer: A Network for Controllable Synthesis and Interpolation of Texture

, 2019
This paper addresses the problem of interpolating visual textures. We formulate this problem by requiring (1) by-example controllability and (2) realistic and smooth interpolation among an arbitrary number of texture samples.
Amirghodsi, Sohrab, Barnes, Connelly, Lukac, Michal, Shechtman, Eli, Yu, Ning   +4 more
core   +1 more source

Contouring with uncertainty [PDF]

, 2008
As stated by Johnson [Joh04], the visualization of uncertainty remains one of the major challenges for the visualization community. To achieve this, we need to understand and develop methods that allow us not only to consider uncertainty as an extra ...
Allendes Osorio, R.S., Brodlie, K.W.
core   +1 more source

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

FEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel, A. F. Volker Wagner, R. Gary Sawers   +2 more
wiley   +1 more source

Real Time Animation of Virtual Humans: A Trade-off Between Naturalness and Control [PDF]

, 2010
Virtual humans are employed in many interactive applications using 3D virtual environments, including (serious) games. The motion of such virtual humans should look realistic (or ‘natural’) and allow interaction with the surroundings and other (virtual ...
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core   +3 more sources

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source