Results 61 to 70 of about 484,275 (334)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Bergman interpolation on finite Riemann surfaces. Part I: Asymptotically Flat Case [PDF]

open access: yes, 2015
We study the Bergman space interpolation problem of open Riemann surfaces obtained from a compact Riemann surface by removing a finite number of points.
Varolin, Dror
core  

k-Space Deep Learning for Reference-free EPI Ghost Correction

open access: yes, 2019
Nyquist ghost artifacts in EPI are originated from phase mismatch between the even and odd echoes. However, conventional correction methods using reference scans often produce erroneous results especially in high-field MRI due to the non-linear and time ...
Han, Yoseob   +4 more
core   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

open access: yesFEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó   +7 more
wiley   +1 more source

On a Class of Hermite Interpolation Polynomials for Nonlinear Second Order Partial Differential Operators

open access: yesEPJ Web of Conferences, 2018
This article is devoted to the problem of construction of Hermite interpolation formulas with knots of the second multiplicity for second order partial differential operators given in the space of continuously differentiable functions of two variables ...
Yanovich Leonid A., Ignatenko Marina V.
doaj   +1 more source

Identification of amino acids essential for angulin‐1/3 binding of the tricellular tight junction binder, angubindin‐1

open access: yesFEBS Open Bio, EarlyView.
Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu   +8 more
wiley   +1 more source

Some Notes on Error Analysis for Kernel Based Regularized Interpolation

open access: yesInternational Journal of Analysis and Applications, 2020
Kernel based regularized interpolation is one of the most important methods for approximating functions. The theory behind the kernel based regularized interpolation is the well-known Representer Theorem, which shows the form of approximation function in
Qing Zou
doaj  

Research on 3D modeling method of complex rock strata surfaces based on unit divisio

open access: yesGong-kuang zidonghua, 2017
In view of the problem that existing 3D modeling method of rock strata surfaces does not systematically consider the construction of 3D modeling of complex rock strata surfaces with geological conditions such as fault and collapse column, horizontal ...
LIU Yong, CUI Hongqing
doaj   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

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