Results 181 to 190 of about 2,806,410 (297)
A $t$-motivic interpretation of shuffle relations for multizeta values [PDF]
Huang Wei-cheng
openalex +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Knowledge based interpretation of moorland in aerial images
Kian Pakzad, Christian Heipke
openalex +2 more sources
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Easing the transition into pathology residency: four years of experience implementing and optimizing an integrated anatomic pathology onboarding course tied to core ACGME competencies. [PDF]
Poljak D, Bryant B, Zhang B, Balla A.
europepmc +1 more source
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel +9 more
wiley +1 more source
Sepsis outbreak following a probable extrinsic contamination of propofol by Escherichia coli, Geneva, 2024. [PDF]
Petrucci R +14 more
europepmc +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Cost-effectiveness analysis of AI-assisted chest X-ray interpretation tools for TB screening: a rapid HTA. [PDF]
Raval D +7 more
europepmc +1 more source

