Results 141 to 150 of about 1,139 (284)

Artificial Intelligence in Exams by Image: Ethical Pros and Cons. [PDF]

Healthcare (Basel)
Zachini C, Nunes S, Rego F, Nunes R.
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

The role of section 2(1) and (4) of the European Communities Act and section 3(1) of the Human Rights Act in the interpretation and application of primary legislation: impact on judicial attitudes to the traditional concept of parliamentary sovereignty

The main aim of this thesis is to examine, through an analysis of relevant case law, the way in which the courts interpret and apply primary legislation pursuant to the interpretative obligation contained in section 2(1) and (4) of the European ...
Okorodas, Anthony
core  

I'm still here and my opinion matters: a scoping review on the experience of epistemic injustice among people living with dementia. [PDF]

Curr Psychol
Calabrese L, Brigiano M, Quartarone M, Chirico I, Trolese S, Lambiase F, Forte L, Annini A, Bortolotti L, Chattat R.   +9 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Contracts for the supply of digital content and digital services

openLa tesi analizza l’impatto delle direttive UE/2019/770 e UE/2019/771 nella costruzione di un mercato unico digitale e nella tutela del consumatore nei contratti di fornitura di contenuti e servizi digitali. Viene approfondito il ruolo del consenso al
GOLA, NICOLO'
core  

Enduring the Unbearable-A Phenomenological Hermeneutical Study on Nurses' Lived Experiences of Stress During the COVID-19 Pandemic. [PDF]

Scand J Caring Sci
Carnesten H, von Heideken Wågert P, Wiklund Gustin L, Skoglund K, Andreae C.   +4 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Living with the incoherent: Practical insights on implementing European restoration policies for biodiversity policy integration. [PDF]

Ambio
Pröbstl F, Zinngrebe Y, Böcher M, Schmid S, Scholz M, Stammel B, Hüesker F.   +6 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source