Results 211 to 220 of about 239,862 (283)

Observational Study on Enhancing End-of-Life Care Competence Through OSCE: Educational Implications. [PDF]

Med Sci Educ
Mora-Delgado J, Lojo-Cruz C, Bández MJ, Rosety-Rodríguez M, García ÁE.   +4 more
europepmc   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

'Pretty devastating': exploring horse owner and veterinarian lived experiences of the equine Hendra virus. [PDF]

Front Vet Sci
White J, Thompson K, van den Berg D, O'Neill G, Mendez DH, Talwar J, Degeling C, Forsythe R, Durrheim DN.   +8 more
europepmc   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Evaluating co-design processes used in the development of healthcare interventions in residential aged care: a scoping review. [PDF]

J Public Health (Oxf)
Westworth SE, Lu A, Long KM, Andrew NE.
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Evolution of the Canadian regulatory system for plant biotechnology. [PDF]

Front Bioeng Biotechnol
Luque L, Hubert J.
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Towards a European End-of-Life Regulation: A Necessary Analysis. [PDF]

Healthcare (Basel)
Orsini F, Cioffi A, Cipolloni L, Bosco MA, Fabrello C, Cecannecchia C, De Simone S.   +6 more
europepmc   +1 more source

Bridging jurisdictions and legislatures: an LLM ensemble and arbiter framework for automated legal risk triage in digital media. [PDF]

Front Artif Intell
Lipianina-Honcharenko K, Drakokhrust T, Bykovyy P, Turchynov K, Ihnatiev I.   +4 more
europepmc   +1 more source