Results 41 to 50 of about 26,187 (263)

Reconstructing ‘the Alcoholic’: Recovering from Alcohol Addiction and the Stigma this Entails [PDF]

open access: yes, 2014
Public perception of alcohol addiction is frequently negative, whilst an important part of recovery is the construction of a positive sense of self.
Leeming, Dawn, Hill, Jodie V.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Pacifism in Mengzian Political Philosophy

open access: yesAsian Studies
This paper reviews the prevalent interpretative approaches to Mengzi’s political philos­ophy in contemporary academia, including realism, just war theory, and just war paci­fism, and proposes an alternative interpretative framework based on positive ...
Yuchen Guo
doaj   +1 more source

DEFINITION, EXPLANATION, AND SCIENTIFIC METHOD IN ARISTOTLE’S DE SOMNO

open access: yesManuscrito, 2019
Exploring the systematic connections between Aristotle’s theory and practice of science has emerged as an important concern in recent years. On the one hand, we can invoke the theory of the Posterior Analytics to motivate specific moves that Aristotle ...
ANDREA FALCON
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Review: Gabriele Rosenthal (2005). Interpretative Sozialforschung. Eine Einführung [Interpretative Social Research: An Introduction]

open access: yesForum: Qualitative Social Research, 2008
"Interpretative Sozialforschung. Eine Einführung" ["Interpretative social research: An Introduction"] by Gabriele ROSENTHAL introduces the methods of and background to interpretative social research.
Matthias Kötter
doaj  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

To some aspects of the Ondruš ´s book of poems Mužské korenie (A male pepper after) three decades [PDF]

open access: yesSlovenska Literatura, 2002
The author of the text takes attention to the “jubilee commemorated “ book of poems by Ján Ondruš Mužské korenie po troch desaťročiach (A male pepper after three decades), mainly to the final poetic composition Chodec po povraze (A walker on the rope ...
Zoltán Rédey
doaj  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Knowledge of education as a framework of interpretation of the Theory of Education as a discipline

open access: yesTendencias Pedagógicas, 2015
This work tries to establish the limits ofTheory ofEducation within the framework of Knowledge Education, as well as considering that Theory of Education is part of that knowledge.
Antonio Rodríguez Martínez
doaj  

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