Results 91 to 100 of about 309,034 (308)
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
EL DESTINO DEL TAHUANTINSUYO EN MANOS DE UN INTÉRPRETE
Resumen: La reconstrucción de los hechos acaecidos en Cajamarca el 16 de noviembre de 1532 exige describir el cuadro de situación con respecto al encuentro de dos culturas totalmente diferentes, el Imperio Incaico y el Español.
Óscar Ferreiro Vázquez
doaj
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Equal Access to Make Emergency Calls: A Case for Equal Rights for Deaf Citizens in Norway and Sweden
It is stipulated that deaf citizens have equal right to use social services as other citizens. One social service is the access to make an emergency call. Deaf citizens who cannot hear and use a signed language to communicate have to make emergency calls
Camilla Warnicke
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Amalia -- A Unified Platform for Parsing and Generation [PDF]
Contemporary linguistic theories (in particular, HPSG) are declarative in nature: they specify constraints on permissible structures, not how such structures are to be computed.
Francez, Nissim +2 more
core +3 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of associative potential in creation and interpretation of trademarks’ names processes
The subject of trademark associative potential is considered. The study is conducted on the material of English, Russian and French. All the hypotheses are exemplified by trademark names of perfumery, cosmetics and household chemistry. The main aim is to
Kseniya Aleksandrovna DZYUBA
doaj

