Results 91 to 100 of about 377,962 (403)

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Legal interpreters in the news in Ireland [PDF]

open access: yes, 2011
This article consists of a review of court reports from national and provincial newspapers in Ireland from 2003 to 1st August 2010. The reports provide an insight into the attitudes of judges, lawyers and police officers to defendants who are not ...
Phelan, Mary
core  

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

Challenges of Refugee Health Care: Perspectives of Medical Interpreters, Case Managers, and Pharmacists

open access: yesJournal of Patient-Centered Research and Reviews, 2018
Purpose: Our objective was to identify perceived challenges in the provision of health care for refugees from the perspective of medical interpreters, case managers, and pharmacists working with refugee patients in Milwaukee, Wisconsin.
Fabiana Kotovicz, Anne Getzin, Thy Vo
doaj   +1 more source

Situated learning in translator and interpreter training: bridging research and good practice

open access: yesSituated Learning in Translator and Interpreter Training, 2016
This issue sets out to gauge the extent to which different embedding systems influence the implementation of Situated Learning models. Situated Learning is generally understood as a context-dependent approach to translator and interpreter training under ...
Maria González-Davies   +1 more
semanticscholar   +1 more source

Interpreting in Northern Ireland [PDF]

open access: yes, 2010
This article examines how interpreter provision in Northern Ireland developed in a very different way from Ireland or indeed England, Scotland or Wales.
Phelan, Mary
core  

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

Theatrical Interpreting in Polish Sign Language

open access: yesPółrocznik Językoznawczy Tertium, 2020
The article explores the topic of theatrical interpreting, a type of interpreting that has been developing dynamically for the last few years, enabling Deaf people to participate in the surrounding culture of the hearing society.
Magda Schromová   +1 more
doaj   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

open access: yesFEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil   +5 more
wiley   +1 more source

Programming with a Differentiable Forth Interpreter [PDF]

open access: yes, 2017
Given that in practice training data is scarce for all but a small set of problems, a core question is how to incorporate prior knowledge into a model. In this paper, we consider the case of prior procedural knowledge for neural networks, such as knowing
Bošnjak, Matko   +3 more
core   +2 more sources

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