Results 141 to 150 of about 147,793 (331)
ŞiHABUDDiN es-SiVASi: HAYATI VE iLMi ŞAHSiYETi
Şihabuddin es-Sivasi, Anadolu'nun siyasi, iktisadi ve kültürel bakımdan oldukça hareketli. bir döneminde yetişmiş önemli simalardan biridir. Sivas'ta başladığı ilmi hayatını Ayasluğ yani, bugünkü !zmir iline bağ lı Selçuk ilçesinde noktalamıştır ...
Bahattin DARTMA
doaj
Chinese commemorative practices in an English graveyard – observations on the Elswick gravestones
This paper explores the contemporary use, for commemorative purposes, of Chinese heritage situated outside of China, in the built environment of Newcastle-upon-Tyne (United Kingdom).
Bruce Davenport, Yuan Zhang, Andrew Law
doaj +1 more source
National Estimates of Professional Interpreter Use in the Ambulatory Setting
Lucy B. Schulson, T. Anderson
semanticscholar +1 more source
Interpreting People and Interpreting Texts
What is the relation between interpreting a person's speech and actions, on the one hand, and interpreting a written text, on the other? That question is considered in connection with the theories of interpretation offered by Donald Davidson and Paul Ricoeur. There are some important similarities between those theories.
openaire +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source

