Results 241 to 250 of about 40,737 (317)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Mode splitting in optical microcavities for speckle-free wavelength reconstruction. [PDF]

Light Sci Appl
Saetchnikov I, Tcherniavskaia E, Ostendorf A, Saetchnikov A.   +3 more
europepmc   +1 more source

CHALLENGES AND INNOVATIONS IN SIMULTANEOUS INTERPRETER TRAINING IN CHINESE UNIVERSITIES: THE ROLE OF TECHNOLOGY IN MODERN PEDAGOGY

Nargiza Ismatullayeva, Mavluda Qosimova
openalex   +2 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

An exploration of the costs of family and group conferencing pathways in adult social care and mental health: A scenario-based cost analysis. [PDF]

PLoS One
Liu L, Tew J, Mahesh S, Kinghorn P.
europepmc   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Language History Collection in Multilingual Clinical Practice: A Qualitative Analysis of Public-Sector Clinical Perspectives. [PDF]

Int J Lang Commun Disord
Leung KI, Westmacott R, Rochon E, Molnar M.   +3 more
europepmc   +1 more source

Understanding preferences for behaviour change support as part of the NHS Health Check: a qualitative study with adults from underserved minoritised ethnic communities. [PDF]

BMJ Open
Griffiths S, Bartlett YK, French DP, McMillan B.   +3 more
europepmc   +1 more source

Prevalent Diagnosed Depression in Relation to Contextual Isolation Among Nursing Home Residents in the United States: A Cross-Sectional Study. [PDF]

J Appl Gerontol
Jesdale BM, Yuan Y, Nielsen NN, Lapane KL.   +3 more
europepmc   +1 more source