A Development of the Interpreter Type Simulator for Cellular Automata
Yuhei Akamien +2 more
openalex +2 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Nurses' Experiences of Working With Healthcare Interpreters When Caring for Patients With Limited Proficiency in the Primary Language: A Qualitative Systematic Review. [PDF]
Seremetkoska M +5 more
europepmc +1 more source
Beyond Neutrality: the Translator-Interpreter and the Right to Asylum in Britain.
Jacob Lagnado
openalex +2 more sources
RAS‐targeted therapies have become a clinical reality. Although promising results in patients have been achieved, there are still challenges ahead such as coping with drug resistance. Here we summarize selected RAS inhibitors targeting either individual KRAS mutant isoforms (KRASG12C, KRASG12D, KRASG12V) or exhibiting a wider inhibitory spectrum ...
Matthias Drosten, Mariano Barbacid
wiley +1 more source
A guide to reactive oxygen species in tumour hypoxia: measurement and therapeutic implications
Hypoxia reshapes tumour redox landscapes by altering compartmental ROS production (mitochondria, NOX, ER, peroxisomes). Accurate interpretation requires oxygen‐contextualised measurement (live biosensors, chemical probes, EPR, LC–MS) and awareness of artefacts (reoxygenation, probe specificity).
Lina Hacker +3 more
wiley +1 more source
Forensic psychiatric care professionals' experiences of communicating with foreign patients and their relatives: the importance of language and culture. [PDF]
Rahman OA +4 more
europepmc +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Disparity in immigrant compulsory care assignment: discrimination or response to treatment need. [PDF]
Segal SP, Badran L, Rimes L, Lakra V.
europepmc +1 more source

