RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Analysis of factors influencing MOOC quality based on I-DEMATEL-ISM method
Systems and Soft ComputingThe quality of MOOCs is influenced by multiple factors. This paper proposes a new method, I-DEMATEL-ISM, which combines intuitionistic fuzzy sets with DEMATEL (Decision testing and evaluation laboratory) and ISM (Interpretive structural modeling), to ...
Liang Zhou, Mingyun Tang, Jian Liu
doaj +1 more source
Interpretive structural modeling (ISM) of risk management in Iran's construction industry [PDF]
مدیریت نوآوری و راهبردهای عملیاتیPurpose: Investment in the construction industry can only cause economic growth and achieve economic results when capital injection and housing production are targeted and ultimately lead to housing consumption; because if the imported funds are not ...
Hamed Shokri, Abbas Afrazeh
doaj +1 more source
Research Methodologies for Management Sciences & Interdisciplinary Research in Contemporary World [PDF]
The charismatic trend attributed in the domain of interdisciplinary research and management sciences has resulted in the notable increase of research activities in these fields.
Hasan, Syed Akif +2 more
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Interpretive structural modeling of political behavior management based on citizenship behavior [PDF]
رویکردهای نوین در مدیریت و بازاریابیThe present study aims to investigate the interpretive structural modeling of political behavior management based on citizenship behavior. The method of this research is applicable in terms of purpose, and qualitative in terms of method type.
Hamidreza Namjofared +4 more
doaj +1 more source
Designing Adaptive Business Model Using Interpretive Structural Modelling
کاوشهای مدیریت بازرگانی, 2015 Due to the expansion of international trade and presence of companies in the foreign markets for exploitation of opportunities, it seems essential to take into account the differences among the markets and countries and adapt their businesses to the specific conditions of each target market.
Hadi Bastam +3 more
openaire +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Modelo de relações entre os riscos que afetam a implantação de produção enxuta
Gestão & ProduçãoResumo O baixo índice de sucesso e as mudanças estruturais e organizacionais necessárias para a Implantação da Produção Enxuta (IPE) indicam a necessidade do uso da abordagem de Gestão de Riscos (GR) para gerenciar esta transformação.
Giuliano Almeida Marodin +3 more
doaj +1 more source
Presenting a Quaternary Prevention Model for the Rural Family Physician Program in Iran with an Interpretive Structural Modeling Approach. [PDF]
Int J Prev Med, 2023 GhorbaniNia R +4 more
europepmc +1 more source