Results 221 to 230 of about 350,628 (274)

Promoter Hypermethylation‐Induced Silencing of FXYD1 Drives Breast Cancer Metastasis via DDX5‐Mediated Wnt/β‐Catenin Pathway Activation

Advanced Science, EarlyView.
This study identifies FXYD1 as an epigenetically silenced tumor suppressor in breast cancer. DNA methylation turns off the gene FXYD1 in breast cancer, and low levels predict worse outcomes. Restoring FXYD1 limits breast cancer cells proliferation and metastasis. In the nucleus, FXYD1 recruits the E3 ligase MAEA to K63‐ubiquitinate DDX5 for proteasomal
Ping Wen, Fanli Qu, Long Wang, Qing Shao, Sisi Li, Yang Qin, Dongping Jiang, Senmiao Zhang, Jiangdong Sui, Guanwen Wang, Ningning Zhang, Xiaohua Zeng   +11 more
wiley   +1 more source

When Stability Fails: Rare Very Late Dislodgement of 3830 Lead. [PDF]

Clin Case Rep
Kumar D, Ghosh N, Halder A, Chakraborty R, Kulshrestha S, De A.   +5 more
europepmc   +1 more source

Cryoablation Activates the cGAS–STING‐CXCL10 Axis in Macrophages to Enhance Anti‐Tumor Immunity in NSCLC

Advanced Science, EarlyView.
Tumor dsDNA released by cryoablation is taken up by macrophages, activating the cGAS‐STING signaling pathway. This leads to an expansion of the CXCL10+ macrophage pool and increased secretion of CXCL10, which in turn recruits CXCR3+ T cells from draining lymph nodes into the tumor microenvironment to exert anti‐tumor effects.
Xinxin Zhi, Zhengcao Xing, Libo Luo, Jiale Wang, Xinyu Liu, Jia Yu, Jizhong Yin, Bin Chen, Yiwei Liu, Hui Sun, Guanghui Gao, Lei Wang, Xiaoxia Chen, Fei Li, Hu Ma, Lin Wang, Shuo Yang, Shengxiang Ren   +17 more
wiley   +1 more source

From Technical Pitfall to Clinical Consequences: Leadless Pacing as a Rescue Solution. [PDF]

Reports (MDPI)
Cacciapuoti F, Mauro C, Casolaro F, Torsi A, Crispo S, Volpicelli M.   +5 more
europepmc   +1 more source

Standard work tools for managing pediatric baclofen pump infections and withdrawal. [PDF]

Childs Nerv Syst
Jain R, Weiss BE, Snider E, Mossner JM, Raskin JS.   +4 more
europepmc   +1 more source

Toward a science of human-AI teaming for decision making: A complementarity framework. [PDF]

PNAS Nexus
Gonzalez C, Donahue K, Goldstein DG, Heidari H, Jalali MS, Schelble B, Singh A, Woolley AW.   +7 more
europepmc   +1 more source

Pheochromocytoma presenting as suspected peripartum cardiomyopathy with ventricular tachyarrhythmias. [PDF]

HeartRhythm Case Rep
Talbot N, Kyrouac D, Patel N.
europepmc   +1 more source