Results 41 to 50 of about 93,735 (304)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Chronic Obstructive Pulmonary Disease in Sweden: An intersectional multilevel analysis of individual heterogeneity and discriminatory accuracy

SSM: Population Health, 2018
Socioeconomic, ethnic and gender disparities in Chronic Obstructive Pulmonary Disease (COPD) risk are well established but no studies have applied multilevel analysis of individual heterogeneity and discriminatory accuracy (MAIHDA) within an ...
Sten Axelsson Fisk, Shai Mulinari, Maria Wemrell, George Leckie, Raquel Perez Vicente, Juan Merlo   +5 more
doaj   +1 more source

INTERSECTIONAL PERSPECTIVES OF HUMAN ANIMAL COMMUNICATION

International Journal of Humanities and Educational Research, 2021
This study aims at reviewing a bulk of related studies, and some verses from the Holly Qur'an in order to discover some mysteries of human animal communication. We believe that the majority of the previous studies concern themselves with human attempts to teach human speech to animals.
openaire   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Habitabilidad urbana y percepción de seguridad en el espacio público desde la perspectiva interseccional

Area
Esta investigación tiene como objetivo evaluar la habitabilidad urbana de los espacios públicos y su relación con la percepción de seguridad en el centro de la ciudad de Xalapa, incorporando la perspectiva interseccional que permite reconocer los grupos ...
Valeria Cruz Ros
doaj   +1 more source

“The Witch’s Mirror”: A Review of Scholarship on Witchcraft and a Reassessment Based on the Intersectional Lived Experiences of Dalits and Adivasis

Religions, 2023
This article explores intersectionality of identities within Dalit and Adivasi traditions through a review of contemporary research on practices of witchcraft.
Jolanda Brunnekreef
doaj   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Overlooked Intersection of Gender and Racial/Ethnic Dimensions in Slovenian Academic Sexual Harassment & Violence Policies

Annales, Series Historia et Sociologia
This article addresses the need to adopt an intersectional perspective when discussing sexual harassment and violence in academia. The introduction of an intersectional perspective is important since sexual harassment and violence in relation to racial ...
Lucija Dežan, Mateja Sedmak, Zorana Medaric   +2 more
doaj   +1 more source

Discrimination against Roma women in Romania. An intersectional perspective [PDF]

, 2019
open2noStill nowadays Roma communities in Romania experience social and spacial marginalization from the rest of the population. Numerous documents and reports underline how, as a consequence of the vicious cycle of poverty, discrimination and social ...

core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source