Results 41 to 50 of about 134,630 (280)

Moving beyond the ‘language problem': developing an understanding of the intersections of health, language and immigration status in interpreter-mediated health encounters [PDF]

open access: yes, 2019
Health systems internationally are dealing with greater diversity in patient populations. However the focus on ‘the language problem’ has meant little attention is paid to diversity within and between migrant populations; and how interpreted ...
Alison Phipps   +17 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

The Impact of White Supremacy on First-Generation Mixed-Race Identity in Post-Apartheid South Africa

open access: yesGenealogy
South African white supremacy has been shaped by over 400 years of settler colonialism and white minority apartheid rule to craft a pervasive and entrenched legacy of privilege and oppression in the post-apartheid context.
Jody Metcalfe
doaj   +1 more source

Charting Relations between Intersectionality Theory and the Neurodiversity Paradigm

open access: yesDisability Studies Quarterly, 2017
This essay explores central elements and applications of intersectionality theory and the neurodiversity paradigm. First, the histories and tenets of intersectionality theory and neurodiversity paradigm are provided.
Lauren Rose Strand
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Beyond the Trinity of Gender, Race and Class

open access: yesEuropean Journal for Research on the Education and Learning of Adults, 2021
Research exploring the gendered dimensions of adult learning has blossomed in the past two decades. Despite this trend, intersectional approaches in adult learning, research, and teaching remain limited primarily to the three categories of gender, race,
Cindy Hanson, Amber Fletcher
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Intersectionality queer studies and hybridity: methodological frameworks for social research [PDF]

open access: yes, 2012
This article seeks to draw links between intersectionality and queer studies as epistemological strands by examining their common methodological tasks and by tracing some similar difficulties of translating theory into research methods. Intersectionality
Fotopoulou, Aristea
core   +4 more sources

Between the waves: currents in contemporary feminist thought [PDF]

open access: yes, 2015
With a continuing focus on liberal feminism, Marxist feminism and essentialism, one would be forgiven for thinking that feminist theory is unable to break free from the ‘second wave’. This is not the case.
Hague, R
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

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