An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids
This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto +6 more
wiley +1 more source
Extreme heat disproportionately increases severe road traffic crashes in high conflict settings and among vulnerable road users in California. [PDF]
Hsu CK +3 more
europepmc +1 more source
We introduce an additively manufactured bioreactor with a perfusion flow system and integrated temperature and pH sensors for skeletal muscle tissue biofabrication. The bioreactor's performance was evaluated by assessing the viability, spreading of the myoblast cells in a printed scaffold, and contraction of the isolated murine musculi interossei ...
Lys Sprenger +9 more
wiley +1 more source
Intersectional dimensions of stigma in neglected tropical diseases: a systematic review of evidence and implications for equity-based health policy. [PDF]
Dejene K, Kühner S.
europepmc +1 more source
Reorganization of Spinal Cord Microarchitecture by Bioluminescent Optogenetic and Rehabilitative Interventions. [PDF]
Ageeva T +6 more
europepmc +1 more source
Brainstem Astrocytes Regulate Estrus-Dependent Oscillations in Food Intake. [PDF]
Ozkaya KS +4 more
europepmc +1 more source
Pronounced Neuroplasticity in the Primary Visual Cortex of the 13-Lined Ground Squirrel during Hibernation. [PDF]
Fultz A +7 more
europepmc +1 more source
Automatic and Real-Time Surgeon's Gazing Point Detection From Surgical Videos Using Machine Learning and Mathematical Algorithm. [PDF]
Sasaki S +9 more
europepmc +1 more source
Patch-Based Ray Tracing in NanoShaper Boosts Molecular Surface Computation. [PDF]
Mazzeo MD +3 more
europepmc +1 more source

