Results 61 to 70 of about 56,200 (271)

Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function. [PDF]

, 2019
With extended stays aboard the International Space Station (ISS) becoming commonplace, there is a need to better understand the effects of microgravity on cardiac function. We utilized human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)
Agrawal, Azakie, Baio, Becker, Bergmann, Burridge, Camberos, Connor, Drosatos, Fermini, Fritsch-Yelle, Garrett-Bakelman, Gauthier, Huebsch, Hughson, Jha, Kim, Kwon, Oikonomopoulos, Perhonen, Rogers, Sharma, Sharma, Sharma, Sides, Spotnitz, Sun, Thomason, Wnorowski, Wu, Yu   +30 more
core   +1 more source

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

Advanced Science, EarlyView.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv, Yi Liu, Ning Xu, Xiao Zhang, Yaming Yang, Chengyao Li, Hanhai Mao, Mingyuan Liu, Xiaolei Liu   +8 more
wiley   +1 more source

A cancer cell-line titration series for evaluating somatic classification. [PDF]

, 2015
BackgroundAccurate detection of somatic single nucleotide variants and small insertions and deletions from DNA sequencing experiments of tumour-normal pairs is a challenging task.
Beck, Timothy, Brown, Andrew MK, Denroche, Robert E, McPherson, John D, Mullen, Laura, Stein, Lincoln, Timms, Lee, Yung, Christina K   +7 more
core   +2 more sources

Species Dependent Toxicity Comparison Outcome

Advanced Science, EarlyView.
By quantitatively assessing and comparing toxicity responses across different animal species and material compositions, our data reveal that toxicity rankings among different materials may be reversed across species. ABSTRACT Toxicity comparison plays a crucial role in material selection across diverse application fields.
Lian Xiao, Zhan Yu, Sihang Liu, Yuheng Liu, Chong Deng, Yugang Zhao, Yi Huang, Zhi‐Gang Zheng   +7 more
wiley   +1 more source

Multistep kinetic self-assembly of DNA-coated colloids

, 2013
Self-assembly is traditionally described as the process through which an initially disordered system relaxes towards an equilibrium ordered phase only driven by local interactions between its building blocks.
Di Michele, Lorenzo, Eiser, Erika, Foffi, Giuseppe, Kotar, Jurij, Nathan, Simon H., Varrato, Francesco   +5 more
core   +1 more source

Chitosan‐Carbon Dot Composite Materials Form a Leaf Surface Barrier to Mitigate the Enrichment and Invasion of Nanoplastics: From Leaf Interface to Systemic Response

Advanced Science, EarlyView.
Foliar spraying of CS‐CDs can form a film on the leaves of Brassica rapa, effectively reducing the enrichment and absorption of PS in the leaves, while increasing the biomass and nutrient content of the plants. In addition, CS‐CDs can also enrich the interfoliar microbial community and activate the plant's own defense metabolic pathways.
Beibei Zhao, Mei Li, Mengjiao Fan, Chuanhuan Liu, Jie Jiang, Jia Song, Yingzhu Liu   +6 more
wiley   +1 more source

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

Angewandte Chemie, EarlyView.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

Inverz szóráselméleti kutatások = Problems of inverse scattering theory [PDF]

, 2009
Kifejlesztettünk egy új fix-energiás inverz kvantum szórás módszert. Szórási adatok invertálására alkalmassá tettük a Cox-Thompson inverz kvantum szórás eljárást. Bose-kondenzátumok ütközéséből származó fázistolás adatokból határoztunk meg effektív Rb-Rb
Apagyi, Barnabás, Horváth, Miklós, Lévay, Péter Pál, Schumayer, Dániel, Szilágyi, András   +4 more
core  

Mitotic spindle scaling during Xenopus development by kif2a and importin α. [PDF]

, 2012
Early development of many animals is characterized by rapid cleavages that dramatically decrease cell size, but how the mitotic spindle adapts to changing cell dimensions is not understood.
HEALD, Rebecca, Wilbur, Jeremy
core   +2 more sources

Wireless, Adaptable and Fully Implantable Battery‐powered Devices for Optical Stimulation of the Spinal Cord in Small Rodents

Advanced Science, EarlyView.
Current technologies for spinal cord optogenetic stimulation rely on external power sources and face reliability constraints in freely behaving animals. Here, a fully implantable, battery‐powered optoelectronic device is introduced, enabling operation in any selected environment with wireless recharging for months‐long stimulation.
Shahriar Shalileh, Adan Moallemi, Elham Mohseni Vadeghani, Samuel Tretjakov, Brianna Tsuyuki, Alexander Golab, Benjamin Rever, Wolfram Tetzlaff, Dena Shahriari   +8 more
wiley   +1 more source