Results 31 to 40 of about 46,210 (213)
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Frontiers in Plant SciencePlant functional traits reflect the capacity of plants to adapt to their environment and the underlying optimization mechanisms. However, few studies have investigated trade-off strategies for functional traits in desert-wetland ecosystems, the ...
Haobo Shi +11 more
doaj +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Morphological variability of otolith organs in three congeneric Pagellus species
Oceanological and Hydrobiological StudiesMorphological features of sagittal otoliths in Pagellus acarne, P. bogaraveo, and P. erythrinus samples collected from the Aegean Sea were used to assess the variability both between Pagellus species and between otolith pairs employing scanning electron ...
Bostanci Derya +3 more
doaj +1 more source
Conventional niche overlap measurements are not effective for assessing interspecific competition
Frontiers in Ecology and Evolution, 2023 Interspecific competition is notoriously difficult to detect and quantify, especially in species that are wide-ranging or otherwise difficult to track in the wild.
Dennis L. Murray +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li +7 more
wiley +1 more source
Geographic variation in advertisement calls in a tree frog species: gene flow and selection hypotheses. [PDF]
PLoS ONE, 2011 In a species with a large distribution relative to its dispersal capacity, geographic variation in traits may be explained by gene flow, selection, or the combined effects of both.
Yikweon Jang +5 more
doaj +1 more source
Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan +7 more
wiley +1 more source
Advanced Functional Materials, EarlyView.This study introduces selenium‐integrated cyanine dye (Se‐Cyn), with superior photostability, absorption, and photothermal efficiency, outperforming ICG in NIR window. Its nanoparticle form remains stable in water, accumulates in tumors, and enables strong optoacoustic imaging and effective phototherapy outcomes.
Divyesh Shelar +11 more
wiley +1 more source