Results 201 to 210 of about 528,800 (318)

Ultrasound‐Actuated Gene Editing in Human Kidney Organoids

Advanced Science, EarlyView.
Peptide‐stabilized nanoemulsions enable spatially controlled, ultrasound‐triggered delivery of gene‐editing proteins deep within human kidney organoid tissues. Focused acoustic pulses drive droplet vaporization, propelling cargo into target renal cells while preserving native tissue microarchitecture. This non‐viral platform improves both the depth and
Michael A. Miller, Nicole Vo, Utkarsh, Ivan Sokirniy, Justin Pritchard, Benjamin S. Freedman, Scott H. Medina   +6 more
wiley   +1 more source

Acute Exacerbation of Interstitial Lung Disease: A Case Series and a Narrative Literature Review. [PDF]

Adv Respir Med
Czyżak B, Lasota A, Majewski S.
europepmc   +1 more source

Acute interstitial pneumonia in feedlot cattle

Master of ScienceDepartment of Clinical SciencesDaniel U. ThomsonAcute Interstitial Pneumonia (AIP) is a costly issue that affects feedlot cattle, especially during hot and dry summers.
Valles, Jose Antonio
core  

Comparative Oligo‐FISH Mapping Illuminates Chromosomal Evolution Among Rutaceae Species Diverged Over 50 Million Years

Advanced Science, EarlyView.
Oligonucleotide‐based fluorescence in situ hybridization probes were developed in the model citrus species Citrus maxima. These probes were applied to comparative karyotyping across 14 species in the Rutaceae family. This analysis revealed chromosomal evolution in lineages that diverged from Citrus nearly 52 million years ago.
Li He, Hainan Zhao, Xiaoxue Zeng, Zujun Yang, Wenting Li, Guoyan Zhang, Guangrong Li, Jian He, Bin Guan, Jiming Jiang   +9 more
wiley   +1 more source

A Successful Monitoring of a Pregnant Woman Suffering from Mixed Connective Tissue Disease-Associated Interstitial Lung Disease: A Case Report. [PDF]

Int J Womens Health
Cui X, Zhou W, Sun Y, Duan Y, Sun H.
europepmc   +1 more source

Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis

Advanced Science, EarlyView.
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun, Qihong Li, Bixi Wang, Gang Wang, Ying Xue, Yibing Liang, Chenhe Hu, Zhenyu Wang, Xiaoge Gao, Haiheng Xu, Jun Song, Hailong Li, Liantao Li, Xiaoxiao Liu, Patrick Ming‐Kuen Tang, Qing Zhang   +15 more
wiley   +1 more source

BIN1 and ALDH1B1 Deficiency in Colonic Smooth Muscle Drives Mitochondrial Dysfunction and Fibrosis in Slow‐Transit Constipation

Advanced Science, EarlyView.
Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu, Hao Zhang, Wenhao Qiao, Ran Liu, Jie Sun, Xiaopei Li, Qin Li, Dongbo Zhao, Dawei Chen, Jingxin Li, Shuxiao Dong   +10 more
wiley   +1 more source

Awareness and adoption intent of cutaneous interstitial fluid-based biomarkers in autoimmune dermatoses among healthcare students: A descriptive cross-sectional study. [PDF]

Medicine (Baltimore)
Kandasamy G, Orayj K, Asiri R, Alshahrani AM, Alzaydani A, Vasudevan R, Osman HA, Elfadil H, Sharif Y, Abu-Elfotuh K, Mani V, Prabahar K.   +11 more
europepmc   +1 more source

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

Advanced Science, EarlyView.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan, Yechuan Deng, Zixin Hu, Yanwei He, Xinting Feng, Jun Ma, Yisheng Chen, Zhijie Zhao, Jie Mei, Zhiheng Lin, Wei Luo, Zhengyuan Fang, Zhufeng Hu, Kunlun Feng, Xinrong Li, Dan Wu, Bowen Han, James Hoi po Hui, Xuanyong Liu, Chen Chen, Gang Chen, Shiyi Chen, Nirong Bao, Jiajun Qiu, Zhiwen Luo   +24 more
wiley   +1 more source

A prospective cohort study for characterization and predictive factors of long-term POST-COVID interstitial changes. [PDF]

Respir Res
Hernandez-Argudo M, Bordas-Martinez J, Vicens-Zygmunt V, Bermudo G, Suarez-Cuartin G, Del Rio B, Bolivar S, Jofre-Grimaldo H, Llatjós R, Pijuan L, Climent F, Gutierrez Y, López-Monzoni S, Sabater J, Fuset MP, Perez-Fernandez XL, Planas R, Gasa M, Moreno A, Robles-Perez A, Balcells E, Badenes D, Barril S, Gonzalez J, Portillo K, Millan-Billi P, Menendez R, Valenzuela C, Santos S, Montes-Worboys A, Fuentes M, Peñafiel J, Lagarda A, Luburich P, Molina-Molina M.   +34 more
europepmc   +1 more source