Results 31 to 40 of about 445,273 (266)
CT Lilun yu yingyong yanjiuObjective: To assess whether there is a correlation between CT scan severity score and pulmonary function in Interstitial Lung Disease, and provide a more reliable basis for clinical diagnosis and treatment.
Hui GAO +4 more
doaj +1 more source
World experience on the treatment of interstitial diseases of the lungs in children (up-date 2017)
Zdorovʹe Rebenka, 2017 The article shows modern principles of classification, diagnosis and treatment of interstitial lung diseases in children for the practice of pediatricians, family doctors, pediatric pulmonologists, thoracic surgeons, transplantologists. Interstitial lung
M.O. Gonchar, O.L. Logvinova
doaj +1 more source
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Frequency of imaging phenotypes of pulmonary interstitial fibrosis
South African Journal of RadiologyBackground: Evaluation of diffuse interstitial lung disease (ILD) in thoracic imaging is complicated. Radiologists often use a pattern approach to interpretation; however, they are rarely aware of the statistical frequency of disease presentation ...
Wallace T. Miller Jr +6 more
doaj +1 more source
Challenges for Clinical Drug Development in Pulmonary Fibrosis
Frontiers in Pharmacology, 2022 Pulmonary fibrosis is a pathologic process associated with scarring of the lung interstitium. Interstitial lung diseases (ILDs) encompass a large and heterogenous group of disorders, a number of which are characterized by progressive pulmonary fibrosis ...
Eric S. White +4 more
doaj +1 more source
Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach +23 more
wiley +1 more source
Adenocarcinoma of the lung mimicking interstitial lung disease
Gülhane Tıp DergisiAtypical radiologic and clinical patterns may be observed within subgroups of lung adenocarcinoma. A 74-year-old man with progressive dyspnea and productive cough unresponsive to antibiotherapy showed bilateral interstitial changes in the lung parenchyma
Sümeyye Kodalak Cengiz +3 more
doaj +1 more source
Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig +9 more
wiley +1 more source
Respiratory ResearchBackground Sarcoidosis is a systemic granulomatous disease of unknown etiology primarily affecting the lungs. Treatment is needed when disease symptoms worsen and organ function deteriorates.
Raisa Kraaijvanger +6 more
doaj +1 more source
More Knot Worms: Four New Polygordius (Annelida) Species from the Pacific and Caribbean
Diversity, 2020 Polygordius is a clade of marine annelids mainly seen in coarse-grained habitats. They are notable for their smooth bodies, lacking in chaetae or obvious segments, and they resemble Nematoda or Nemertea. Though Polygordius taxa are found in all oceans of
Chrissy A. Tustison +2 more
doaj +1 more source