Results 131 to 140 of about 781,343 (307)

Impact of coal mine dust exposure and cigarette smoking on lung disease in Appalachian coalminers

open access: yesRespiratory Research
Introduction Interactions have been demonstrated between cigarette smoking (CS) and occupational exposures to several particles. This study tested the postulate that CS interacts with coal mine dust exposure to impact and change radiological and ...
Rahul G. Sangani   +6 more
doaj   +1 more source

Profibrotic effect of IL-17A and elevated IL-17RA in idiopathic pulmonary fibrosis and rheumatoid arthritis-associated lung disease support a direct role for IL-17A/IL-17RA in human fibrotic interstitial lung disease.

open access: yesAmerican Journal of Physiology - Lung cellular and Molecular Physiology, 2019
Interleukin (IL)-17 is a T helper 17 cytokine implicated in the pathogenesis of many autoimmune diseases, including rheumatoid arthritis (RA). Although IL-17A has a well-established role in murine pulmonary fibrosis models, its role in the tissue ...
Jie Zhang   +11 more
semanticscholar   +1 more source

MUC5B Promoter Variant and Rheumatoid Arthritis with Interstitial Lung Disease

open access: yesNew England Journal of Medicine, 2018
BACKGROUND Given the phenotypic similarities between rheumatoid arthritis (RA)–associated interstitial lung disease (ILD) (hereafter, RA‐ILD) and idiopathic pulmonary fibrosis, we hypothesized that the strongest risk factor for the development of ...
P. Juge   +71 more
semanticscholar   +1 more source

Lung Cancer and Interstitial Lung Diseases

open access: yesCancers
Lung cancer continues to be one of the leading causes of cancer-related death worldwide. There is evidence of a complex interplay between lung cancer and interstitial lung disease (ILD), affecting disease progression, management strategies, and patient outcomes. Both conditions develop as the result of common risk factors such as smoking, environmental
Fotios Drakopanagiotakis   +6 more
openaire   +2 more sources

Etiology, Risk Factors, and Biomarkers in Systemic Sclerosis with Interstitial Lung Disease

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2019
Systemic sclerosis (SSc) is a complex, multiorgan, autoimmune disease. Lung fibrosis occurs in ∼80% of patients with SSc; 25% to 30% develop progressive interstitial lung disease (ILD).
D. Khanna   +5 more
semanticscholar   +1 more source

A first look at the reliability, validity and responsiveness of L-PF-35 dyspnea domain scores in fibrotic hypersensitivity pneumonitis

open access: yesBMC Pulmonary Medicine
Background Dyspnea impairs quality of life (QOL) in patients with fibrotic hypersensitivity pneumonitis (FHP). The Living with Pulmonary Fibrosis questionnaire (L-PF) assesses symptoms, their impacts and PF-related QOL in patients with any form of PF ...
Jeffrey J. Swigris   +2 more
doaj   +1 more source

P9 Cough Is Prevalent In Higher Proportion Of Older Patients With Both Idiopathic Pulmonary Fibrosis And Non-specific Interstitial Lung Disease [PDF]

open access: bronze, 2014
G. Saini   +7 more
openalex   +1 more source

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