Results 341 to 350 of about 754,612 (422)

Genetic Diagnosis and Clinical Features of Fetuses With Congenital Diaphragmatic Hernia

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective Congenital diaphragmatic hernia (CDH) is a rare abnormality with highly heterogeneous genetic causes. This study investigated chromosomal and monogenic abnormalities in fetal CDH patients and evaluated the efficacy of chromosomal microarray analysis (CMA) and whole‐exome sequencing (WES) for genetic diagnosis.
Yan Lü   +18 more
wiley   +1 more source

CXCL14 increase dendritic cell antigen presentation and promote asthma immune response

open access: yesPediatric Discovery, EarlyView.
RNA‐seq showed that C‐X‐C motif chemokine ligand 14 (CXCL14) was upregulated in bone marrow dendritic cells after house dust mites (HDM) stimulation, and its function was related to signal molecule interaction and the immune system. The expression of CXCL14 was increased in the HDM‐induced allergic asthma model.
Wenjie Wu, Fengxia Ding, Yan Li, Zhou Fu
wiley   +1 more source

Clinical characteristics and risk factors of severe bocavirus‐positive pneumonia in children and a literature review

open access: yesPediatric Discovery, EarlyView.
The study explored the clinical characteristics and risk factors of HBoV‐positive severe pneumonia in children. These findings indicate that HBoV can be identified in respiratory samples from children with severe pneumonia, denoting its role as a viral pathogen in hospitalized children with this condition.
Jing Liao   +6 more
wiley   +1 more source

Diagnostic Utility of Bronchoalveolar Lavage Flow Cytometric Leukocyte Profiling in Interstitial Lung Disease and Infection. [PDF]

open access: yesBiomolecules
Novoa-Bolivar EM   +14 more
europepmc   +1 more source

Recent Progress in Treating Airway Mucus Hypersecretion by Targeting the Epidermal Growth Factor Receptor Signaling Pathway

open access: yesPediatric Discovery, EarlyView.
ABSTRACT Asthma, chronic pulmonary obstructive disease (COPD), cystic fibrosis, and acute respiratory infections are severe respiratory conditions that significantly contribute to global morbidity and mortality. Airway mucus hypersecretion is an important common pathophysiological and clinical manifestation of these diseases and is closely associated ...
Yuanyuan Zhang   +4 more
wiley   +1 more source

Interstitial lung disease: retrospective study of the prognostic impact of acute exacerbations. [PDF]

open access: yesSarcoidosis Vasc Diffuse Lung Dis
Pacheco J   +3 more
europepmc   +1 more source

Microbiota diversity and differences in the respiratory tract of children with pneumonia

open access: yesPediatric Investigation, EarlyView.
Differences in microbial communities in the upper and lower respiratory tract in patients with pneumonia were investigated in this study by sequencing the 16S rRNA genes in pharyngeal swabs and alveolar lavage fluid. Forty‐three subjects were enrolled in the study, and one upper and one lower respiratory tract sample were collected from each subject ...
Dandan Ge   +4 more
wiley   +1 more source

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