Results 351 to 360 of about 754,612 (422)

Patient perspectives on educational needs in scleroderma-interstitial lung disease. [PDF]

J Scleroderma Relat Disord
Savvaides TM, Di Vitantonio TA, Edgar A, O'Beirne R, Krishnan JK, Kaner RJ, Podolanczuk AJ, Spiera R, Gordon J, Safford MM, Lakin KS, Aronson KI.   +11 more
europepmc   +1 more source

Postmarketing Assessment of Antibody–Drug Conjugates: Proof‐of‐Concept Using Model‐Based Meta‐Analysis and a Clinical Utility Index Approach

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Antibody–drug conjugates (ADCs) are a promising class of targeted cancer therapies. However, they need careful dose optimization to maximize effectiveness and minimize side effects. Sometimes, safety issues may only become apparent after approval, so ongoing evaluation is important.
Innocent Gerald Asiimwe, Nour Chtiba, Samer Mouksassi, Goonaseelan (Colin) Pillai, Raimund M. Peter, Eunice Yuen, Venkatesh Pilla Reddy   +6 more
wiley   +1 more source

Pulmonary Hypertension-Related Interstitial Lung Disease: An Expert Opinion with a Real-World Approach. [PDF]

Biomedicines
Criner RN, Naranjo M, D'Alonzo G, Weaver S.   +3 more
europepmc   +1 more source

Mechanistic Physiologically Based Pharmacokinetic Modeling of Dry Powder and Nebulized Formulations of Orally Inhaled TMEM16A Potentiator GDC‐6988

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT The orally inhaled route of administration for respiratory indications can maximize drug exposure to the site of action (lung) to increase efficacy while minimizing systemic exposure to achieve an improved safety profile. However, due to the difficulty of taking samples from different regions of the human lung, often only systemic ...
Rui Zhu, Ian Sorrell, Fang Ma, Miaoran Ning, Yoen‐Ju Son, Gaohong She, Tom De Bruyn, Joshua Galanter, Nastya Kassir, Ryan Owen, Masoud Jamei, Iain Gardner, Yuan Chen   +12 more
wiley   +1 more source

Characterization of Incident Interstitial Lung Disease in Late Systemic Sclerosis. [PDF]

Arthritis Rheumatol
Hoa S, Berger C, Lahmek N, Larché M, Osman M, Choi M, Pope J, Thorne C, Canadian Scleroderma Research Group, Hudson M.   +9 more
europepmc   +1 more source

Malignancies and immunoglobulin G4‐related disease

Rheumatology &Autoimmunity, EarlyView.
Immunoglobulin G4‐related disease (IgG4‐RD) is associated with increased cancer risk. Malignancies affect both IgG4‐RD involved organs, such as the lung, pancreas, bile duct, and prostate, and noninvolved organs, such as the gastrointestinal duct. B‐cell neoplasms constitute a proportion of the malignancies linked to this disease.
Jingna Li, Wen Zhang
wiley   +1 more source

Concurrence of bird-related hypersensitivity pneumonitis and systemic sclerosis-associated interstitial lung disease. [PDF]

Rheumatol Adv Pract
Miyahara M, Matsuda KM, Kotani H, Miyake T, Yoshizaki-Ogawa A, Yoshizaki A, Sato S.   +6 more
europepmc   +1 more source

Artificial intelligence in rheumatoid arthritis

Rheumatology &Autoimmunity, EarlyView.
Advancements in artificial intelligence (AI) over the past 5 years have brought significant progress to the medical field, including rheumatoid arthritis (RA). AI integrates multimodal data, including clinical, imaging, omics, and longitudinal information, to enhance RA diagnosis and treatment.
Yiduo Sun, Jin Lin, Weiqian Chen
wiley   +1 more source

The impact of interstitial lung disease in patients with acid sphingomyelinase deficiency (ASMD) - A case series. [PDF]

Respir Med Case Rep
Costa I Colomer J, Garcia-Moyano M, Maiz L, Perez-Tarazona S, Ruiz de Valbuena M, Ceberio L, Correcher P, Juliá-Palacios N, Morales M, Pérez-Yagüe G, Villarrubia J, Pérez-Rojo R.   +11 more
europepmc   +1 more source

HIV-1 and SIV Infection are associated with early loss of lung interstitial CD4+ T cells and dissemination of pulmonary tuberculosis [PDF]

, 2019
et al,, Khader, Shabaana A
core   +1 more source