Results 81 to 90 of about 36,306 (218)

When to consider an inborn error of immunity: clues for physicians

Internal Medicine Journal, EarlyView.
Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley   +1 more source

Acute tubulo-interstitial nephritis leading to acute renal failure following multiple hornet stings

BMC Nephrology, 2006
Background Hornet stings are generally associated with local and occasionally anaphylactic reactions. Rarely systemic complications like acute renal failure can occur following multiple stings. Renal failure is usually due to development of acute tubular
Bambery Pradeep, Sakhuja V, Mahesha V, Wanchu Ajay, Sharma Aman, Singh Surjit   +5 more
doaj   +1 more source

GLP‐1 Receptor Agonists and Weight Loss: A Critical Review of Mechanisms

Obesity Reviews, EarlyView.
ABSTRACT GLP‐1 receptor agonist medications have the potential to promote marked weight loss, but maximal and sustained benefit may be compromised by poor compliance and cessation of use. Development of next‐generation medications that address current obstacles to effective use and development of effective adjunct treatments will benefit from better ...
Giorgia Rutigliani, Tzu‐Wen L. Cross, Erica de Jong, Emily S. Glover, Ivan D. Mendoza, Mojisola Adisa, Keigo Tomoo, Xinyi Zhou, Richard D. Mattes   +8 more
wiley   +1 more source

Comparative 3‐Year Allograft Outcomes for Recipients of Kidneys From SARS‐CoV‐2 NAT‐Positive Donors

Transplant Infectious Disease, EarlyView.
In this retrospective single‐center study of 220 kidney transplants from SARS‐CoV‐2 NAT+, NAT+ with COVID as cause of death (CoV‐COD) and NATneg donors, we found no significant difference in rejection or kidney pathologies at 1 year, and death, graft loss, or eGFR at 3 years by CoV‐donor status.
Christine E. Koval, Mohamed Eltemamy, Nabin K. Shrestha, Leal Herlitz, Emilio D. Poggio, Alvin C. Wee   +5 more
wiley   +1 more source

Acute interstitial nephritis and drug-induced systemic lupus erythematosus due to chlorthalidone and amiodarone: A case report

SAGE Open Medical Case Reports, 2020
Drug-induced lupus erythematosus has features distinct from primary systemic lupus erythematosus. It can occur with a wide variety of agents that result in the generation of anti-histone or other types of antibodies.
Umut Selamet, Ramy M Hanna, Anthony Sisk, Lama Abdelnour, Lena Ghobry, Ira Kurtz   +5 more
doaj   +1 more source

Expression characteristics of dual‐specificity phosphatase 2 and hypoxia‐inducible factor‐1α in acute kidney injury and preliminary study of the effect of dual‐specificity phosphatase 2 on HK‐2 cells

Experimental Physiology, EarlyView.
ABSTRACT Acute kidney injury (AKI) is a global health problem with significant long‐term harm if the prognosis is poor. Dual‐specificity phosphatase 2 (DUSP2) is involved in key regulatory pathways in several disease processes, but its function in renal pathophysiology is unclear.
Xueqian Chu, Songmin Xue, Lanyan Lin, Xuan Huang, Sisi Chen, Wulaer Adeli, Zulibiya Tuohetiyaer, Suhua Li, Chen Lu   +8 more
wiley   +1 more source

Lansoprazole-induced acute allergic interstitial nephritis in a renal transplant recipient: a case report

, 2012
Drug-induced interstitial nephritis is one of the causes of graft dysfunction in renal transplant recipients. Although commonly implicated as a cause of drug-induced interstitial nephritis in the general population, proton pump inhibitor-induced ...
Yilmaz, Rahmi, Kutlugun, Aysun Aybal, BAYDAR, DİLEK, YILDIRIM, TOLGA, AKI, FAZIL TUNCAY, Turgan, Cetin   +5 more
core   +1 more source

Prosthetic valve endocarditis from Mycobacterium chimaera infection causing granulomatous interstitial nephritis

IDCases, 2020
Mycobacterium chimaera is a rare infection associated with cardiopulmonary bypass. We describe a case of granulomatous interstitial nephritis caused by M. chimaera in a patient with prosthetic aortic valve endocarditis.
Christopher Trautman, Jonathan R. Da Costa, Cherise Cortese, Nabeel Aslam   +3 more
doaj   +1 more source

PPP2R3C serves as a negative regulator associated with reduced T cell hyperactivation and renal protection in lupus

Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.
Downregulation of PPP2R3C in lupus CD4+ T cells unleashes JNK/c‑Jun and PLCγ1 signalling, driving calcium influx and inflammatory cytokine production. Reconstitution of PPP2R3C expression curbs T cell activation, lowers autoantibody levels and alleviates lupus nephritis, highlighting PPP2R3C as a promising therapeutic candidate. Abstract Background CD4+
Xuan Fang, Yi Qin, Jinhui Tao, Zhou Zhou, Minglong Cai, Hong Zhang, Xiangpei Li, Xiaomei Li, Zhu Chen   +8 more
wiley   +1 more source

Acute granulomatous interstitial nephritis and ulcerative colitis: a case report and literature review

Italian Journal of Medicine, 2018
Tubulo-interstitial nephritis (TIN) in patients affected by inflammatory bowel disease, both ulcerative colitis and Crohn’s disease, is usually considered as drug-associated to aminosalicylate.
Giorgia Comai, Olga Baraldi, Vania Cuna, Valeria Corradetti, Maria Cappuccilli, Marco Busutti, Deborah Malvi, Benedetta Fabbrizio, Massimo Campieri, Gaetano La Manna   +9 more
doaj   +1 more source