Results 111 to 120 of about 86,128 (305)

Quantile regression with interval-censored data in questionnaire-based studies [PDF]

, 2022
Angel G. Angelov, Magnus Ekström, Klarizze Puzon, Agustin Arcenas, Bengt Kriström   +4 more
openalex   +1 more source

Clinical Significance of PD‐L1 and HLA Expression in Esophageal Squamous Cell Carcinoma in Response to Immunotherapy

Annals of Gastroenterological Surgery, EarlyView.
This study evaluated immune‐related biomarkers in esophageal squamous cell carcinoma treated with immune checkpoint inhibitors after postoperative recurrence. PD‐L1 expression in tumor‐associated macrophages and tumor cells, together with HLA class I downregulation and HLA‐DR expression, were associated with favorable responses to immunotherapy.
Kosuke Kanemitsu, Yoshiyuki Tagayasu, Yoshihiro Komohara, Cheng Pan, Rin Yamada, Yukio Fujiwara, Kazuto Harada, Keisuke Kosumi, Yoshifumi Baba, Masaaki Iwatsuki   +9 more
wiley   +1 more source

Semiparametric Transformation Models with a Change Point for Interval-Censored Failure Time Data

Mathematics
Change point models are widely used in medical and epidemiological studies to capture the threshold effects of continuous covariates on health outcomes.
Junyao Ren, Shishun Zhao, Dianliang Deng, Tianshu You, Hui Huang   +4 more
doaj   +1 more source

Real‐World Outcomes of Mycosis Fungoides and Site‐Specific Nodal Involvement: A Registry‐Based Study of 25 467 Patients

American Journal of Hematology, EarlyView.
ABSTRACT Mycosis fungoides (MF) is a rare extranodal T‐cell lymphoma with primary cutaneous involvement. While it is the most common primary skin lymphoma, large‐scale real‐world data defining survival benchmarks and the prognostic significance of specific nodal sites remain limited.
Charalampos Filippatos, Alexandros Briasoulis, Evangelos Terpos, Despina Fotiou, Maria Gavriatopoulou   +4 more
wiley   +1 more source

Avoiding drug residues: a multivariate approach to estimating withdrawal intervals in edible tissues of goats following extra label administration of flunixin meglumine

Frontiers in Veterinary Science
IntroductionFlunixin meglumine is a non-steroidal anti-inflammatory drug (NSAID) commonly used extra-label in goats, necessitating the determination of an extended withdrawal interval (WDI) to minimize the risk of violative residues at slaughter. Current
Farha Ferdous Sheela, Jim E. Riviere, Jim E. Riviere, Majid Jaberi-Douraki, Majid Jaberi-Douraki, Jacqueline M. Hughes-Oliver, Ronald E. Baynes   +6 more
doaj   +1 more source

A support vector machine-based cure rate model for interval censored data. [PDF]

Stat Methods Med Res, 2023
Pal S, Peng Y, Aselisewine W, Barui S.
europepmc   +1 more source

The Age at Onset of LRRK2 p.Gly2019Ser Parkinson's Disease Across Ancestries and Countries of Origin

Annals of Neurology, EarlyView.
Objectives The objective of this study was to elucidate differences in the cumulative incidence of Leucine‐rich repeat kinase 2 (LRRK2) p.Gly2019Ser‐related Parkinson's disease (PD; LRRK2‐PD) between ancestries and countries. Methods We included 922 unrelated p.Gly2019Ser variant carriers (affected = 762 and unaffected = 160) from the Global Parkinson ...
Theresa Lüth, Björn‐Hergen Laabs, Sebastian Sendel, Inke R. König, Amke Caliebe, Alastair J. Noyce, Laurel A. Screven, Soraya Bardien, Matthew Farrer, Faycel Hentati, Rim Amouri, Christine Klein, Samia Ben Sassi, Joanne Trinh, Global Parkinson's Genetics Program (GP2)   +14 more
wiley   +1 more source

Blood Lactate as a Prognostic Biomarker for Survival and Weight Loss in Amyotrophic Lateral Sclerosis: An Exploratory–Validation Study

Annals of Neurology, EarlyView.
Objective Lactate is increasingly recognized as an energy substrate, but its relevance to amyotrophic lateral sclerosis (ALS) remains unclear. We examined whether blood lactate is associated with survival and weight loss in ALS. Methods This retrospective study included an Australian exploratory cohort and a Japanese validation cohort with clinical ...
Ryutaro Nakamura, Frederik J. Steyn, Shuhei Kobashi, Nobuhiro Ogawa, Akihiro Kitamura, Isamu Yamakawa, Robert D. Henderson, Shyuan T. Ngo, Makoto Urushitani   +8 more
wiley   +1 more source

Temporal Modeling of Amyloid and Tau Trajectories in Alzheimer's Disease Using PET and Plasma Biomarkers

Annals of Neurology, EarlyView.
Objective This study aimed to compare positron emission tomography (PET) and plasma‐based temporal modeling of amyloid and tau biomarkers in Alzheimer's disease. Methods Longitudinal amyloid PET (n = 1,097, mean age ± SD = 72.5 ± 7.38 year, 51.4% male), 18F‐flortaucipir tau‐PET (n = 230, 74.3 ± 7.18 year, 52.2% female), and Fujirebio Lumipulse plasma p‐
Christopher A. Brown, Katheryn A.Q. Cousins, Magdalena Korecka, Emily McGrew, Alice Chen‐Plotkin, John A. Detre, Corey T. McMillan, Edward B. Lee, Sandhitsu R. Das, Dawn Mechanic‐Hamilton, Paul A. Yushkevich, Ilya M. Nasrallah, Leslie M. Shaw, for the Alzheimer's Disease Neuroimaging Initiative, David A. Wolk   +14 more
wiley   +1 more source

Analyzing Interval-Censored Recurrence Event Data with Adjusting Informative Observation Times by Propensity Scores

Mathematics
In this paper, we discuss the statistical inference of interval-censored recurrence event data under an informative observation process. We establish an additive semiparametric mean model for the recurrence event process.
Ni Li, Meiting Lin, Yakun Shang
doaj   +1 more source