Results 61 to 70 of about 86,128 (305)
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi +9 more
wiley +1 more source
ICBoost: An XGBoost-Based Unbiased Transformed Algorithm for Survival Regression
Prediction models for disease onset are critical in biomedical research and survival analysis. With machine learning methods increasingly being used to handle survival data with censoring, unbiased transformation theory offers an alternative method for ...
Jingyi Zhang +3 more
doaj +1 more source
We consider a regression analysis of multivariate interval-censored failure time data where the censoring may be informative. To address this, an approximated maximum likelihood estimation approach is proposed under a general class of semiparametric ...
Mengzhu Yu, Mingyue Du
doaj +1 more source
Experimental Survival Curves for Interval-Censored Data
A method is given for calculating from interval‐censored data an estimate of the c.d.f. which is analogous to the estimate derivable from right‐censored data by the life‐table technique. A Fortran implementation has been constructed by the author.
openaire +2 more sources
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou +15 more
wiley +1 more source
Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon +5 more
wiley +1 more source
Application and Comparison of Methods for Analysing Correlated Interval-censored Data from Sexual Partnerships [PDF]
Khangelani Zuma, Mark N. Lurie
openalex +1 more source
Sex Differences in Medication Discontinuation in Axial Spondyloarthritis
Objective We examined sex differences in medication discontinuation among patients with axial spondyloarthritis (axSpA) initiating tumor necrosis factor inhibitors (TNFi), interleukin‐17 inhibitors (IL‐17i), or JAK inhibitors (JAKi). Methods Using data from the Rheumatology Informatics System for Effectiveness (RISE) Registry (2003–2025), we assessed ...
Rachael Stovall +9 more
wiley +1 more source
Outcome-dependent Sampling with Interval-censored Failure Time Data [PDF]
Summary Epidemiologic studies and disease prevention trials often seek to relate an exposure variable to a failure time that suffers from interval-censoring. When the failure rate is low and the time intervals are wide, a large cohort is often required so as to yield reliable precision on the exposure-failure-time relationship.
Qingning Zhou, Jianwen Cai, Haibo Zhou
openaire +2 more sources
Objective We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analyzed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalized with AMI between 2005 and 2019 from the Myocardial Ischaemia ...
Megan Butler +8 more
wiley +1 more source

