Results 101 to 110 of about 223,480 (289)

Cutting Through the Green: A Case for Grassland Archaeology Using UAV Multispectral Data

open access: yesArchaeological Prospection, EarlyView.
ABSTRACT Advances in low‐altitude remote sensing are needed to improve the effectiveness of archaeological prospection in the Netherlands. The geomorphological situation and land use history make applying various remote sensing and geophysical technologies particularly challenging.
Roeland Emaus
wiley   +1 more source

Enhancing numerical constraint propagation using multiple inclusion representations [PDF]

open access: yes, 2018
Building tight and conservative enclosures of the solution set is of crucial importance in the design of efficient complete solvers for numerical constraint satisfaction problems (NCSPs).
Faltings, Boi   +2 more
core  

Effect of carbamazepine on the pharmacokinetics of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader, in healthy adults

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim To evaluate the effects of carbamazepine, a strong cytochrome P450 (CYP)3A4 inducer, on the pharmacokinetics and safety of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader. Methods This was a phase 1, open‐label, fixed‐sequence, two‐period study in healthy adult participants.
Hechuan Wang   +7 more
wiley   +1 more source

A Method for Estimating the Resultant Expanded Uncertainty Value Based on Interval Arithmetic

open access: yesApplied Sciences
The article describes a method for determining the resultant expanded uncertainty value in the case of analyzing an uncertainty budget with many components.
Marian Kampik   +2 more
doaj   +1 more source

Robust MPC of constrained nonlinear systems based on interval arithmetic [PDF]

open access: yes, 2005
A robust MPC for constrained discrete-time nonlinear systems with additive uncertainties is presented. The proposed controller is based on the concept of reachable sets, that is, the sets that contain the predicted evolution of the uncertain system for
Alamo, Teodoro   +3 more
core  

Mapping opioid exposure through prescription data and postmortem analysis of opioid drugs in multiple tissues

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background and Purpose Although opioids are central to end of life (EoL) care, tissue‐level opioid exposure remains poorly understood. The objective of this study was to characterize the relationship between prescription‐derived morphine equivalent daily dose (MEDD) and measured morphine concentrations across multiple organs.
Niamh Higgins   +23 more
wiley   +1 more source

Conformity and statistical tolerancing

open access: yesInternational Journal of Metrology and Quality Engineering, 2018
Statistical tolerancing was first proposed by Shewhart (Economic Control of Quality of Manufactured Product, (1931) reprinted 1980 by ASQC), in spite of this long history, its use remains moderate.
Leblond Laurent, Pillet Maurice
doaj   +1 more source

Entropy Analysis of RR and QT Interval Variability during Orthostatic and Mental Stress in Healthy Subjects

open access: yesEntropy, 2014
Autonomic activity affects beat-to-beat variability of heart rate and QT interval. The aim of this study was to explore whether entropy measures are suitable to detect changes in neural outflow to the heart elicited by two different stress paradigms.
Mathias Baumert   +5 more
doaj   +1 more source

A phase 1 evaluation of inhaled oxytocin: Physiologically‐based pharmacokinetic model informed dosing of a novel heat‐stable oxytocin delivery system

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim To develop and validate a physiologically‐based pharmacokinetic (PBPK) model enabling inhaled oxytocin dose selection for clinical evaluation. Subsequently, to conduct a phase 1 study investigating the pharmacokinetics and safety of selected doses of an optimized inhaled oxytocin product in healthy, non‐pregnant female participants.
Pete Lambert   +6 more
wiley   +1 more source

Uncertainty Analysis in the Noise Parameters Estimation

open access: yesMATEC Web of Conferences, 2012
The new approach to the uncertainty estimation in modelling acoustic hazards by means of the interval arithmetic is presented in the paper. In the case of the noise parameters estimation the selection of parameters specifying the acoustic wave ...
Pawlik P., Batko W.
doaj   +1 more source

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