Results 111 to 120 of about 3,598,266 (338)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Implementation and verification of global optimization benchmark problems
Open Engineering, 2017 The paper considers the implementation and verification of a test suite containing 150 benchmarks for global deterministic box-constrained optimization. A C++ library for describing standard mathematical expressions was developed for this purpose.
Posypkin Mikhail, Usov Alexander
doaj +1 more source
Comparing Survival Functions with Doubly Interval-Censored Data: An Application to Diabetes Surveyed by Korean Cancer Prevention Study [PDF]
, 2009 Sun Ha Jee, Chung Mo Nam, Jinheum Kim
openalex +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Cournot oligopoly interval games [PDF]
In this paper we consider cooperative Cournot oligopoly games. Following Chander and Tulkens (1997) we assume that firms react to a deviating coalition by choosing individual best reply strategies.
Aymeric Lardon
core
Predicting Post mortem Interval using Discriminant Function Analysis of the Succession Pattern of Necrophagous Insects [PDF]
, 2017 Azeezat O. Alafia +5 more
openalex +1 more source
Some Important Classes of the Continuous and Complex Interval-Valued Functions
, 2023 Halise Levent, Yılmaz Yılmaz
openalex +2 more sources
Interval conjectures for level Hilbert functions
Journal of Algebra, 2009 We conjecture that the set of all Hilbert functions of (artinian) level algebras enjoys a very natural form of regularity, which we call the {\em Interval Conjecture} (IC): If, for some positive integer $ $, $(1,h_1,...,h_i,...,h_e)$ and $(1,h_1,...,h_i+ ,...,h_e)$ are both level $h$-vectors, then $(1,h_1,...,h_i+ ,...,h_e)$ is also level for each ...
openaire +2 more sources
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source