Results 81 to 90 of about 1,377,441 (267)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Difference Gai Sequences of Interval numbers with respect to Orlicz Function
Acta Scientiarum: TechnologyIn this article we have introduced some classes generalized difference () Gai sequences of interval numbers with Orlicz functions M. We have studied some algebraic and topological properties of the classes of sequences like, linearity, completeness ...
Achyutananda Baruah, Amar Jyoti Dutta
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Annals of Hepatology, 2006 Liver cirrhosis is associated with a wide range of cardiovascular abnormalities. These abnormalities include hyperdynamic circulation characterized by an increase in cardiac output and a decrease in peripheral vascular resistance.
Waleed Al Hamoudi, Samuel S. Lee
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Histological Alterations in Human Skin as a Function of Postmortem Interval
Journal of Forensic Science and MedicineThe determination of time since death (TSD) is one of the important objectives of a forensic autopsy. This narrative review aims to analyze the current literature on histological markers of human skin used to estimate the TSD and to assess their ...
Shiyam Sundar Karunanithy +3 more
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Concerning Nonnegative Valued Interval Functions [PDF]
Proceedings of the American Mathematical Society, 1962 2. Preliminary definitions and theorems. Throughout this paper all integrals considered will be Hellinger [1i type limits of the appropriate sums (the definitions, theorems and proofs of this paper can be extended to "many valued" functions). Thus, if K is a real valued function of subintervals of the number interval [a, b], the existence of f[a,bjK(I)
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source