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Long‐Lasting Auditory and Vestibular Recovery Following Gene Replacement Therapy in a Novel Usher Syndrome Type 1c Mouse Model

open access: yesAdvanced Science, EarlyView.
This study shows that gene replacement therapy using the AAV2/Anc80L65 virus can successfully restore hearing and balance in Ush1c knockout mice. The treatment leads to lasting improvements in both auditory and vestibular functions, highlighting its potential as a therapeutic approach for genetic hearing loss and vestibular disorders in humans ...
Weinan Du   +13 more
wiley   +1 more source

Interval graph mining

International Journal of Data Mining, Modelling and Management, 2018
Frequent subgraph mining is a difficult data mining problem aiming to find the exact set of frequent subgraphs into a database of graphs. Current subgraph mining approaches make use of the canonical encoding which is one of the key operations. It is well known that canonical encodings have an exponential time complexity.
Amina, Kemmar   +2 more
openaire   +3 more sources

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