Results 101 to 110 of about 448,992 (178)

Plasma DNMT1 Activity for Assessing Tumor Burden and Predicting Neoadjuvant Therapy Response in Breast Cancer

Advanced Science, EarlyView.
In this work, a detection method is presented for the activity of plasma DNA methyltransferase 1 (DNMT1), namely DNMT1 Identification by Variable Activity (DIVA). DIVA can detect plasma DNMT1 at levels as low as 10−7 U mL−1, also it successfully evaluated tumor burden and predicted the neoadjuvant therapy responses of breast cancer patients.
Yingran Wang, Guozhi Zhang, Zhizhao Zhang, Mengsi Zhang, Jiao Chen, Ke Wang, Lu Liu, Jing Bao, Ming Chen, Xiaowei Qi, Mingxuan Gao   +10 more
wiley   +1 more source

Framework development of continuous non-linear Diophantine fuzzy sets and its application to renewable energy source selection. [PDF]

Sci Rep
Khan A, Khan S, Rahimzai AA, Abdullah S.
europepmc   +1 more source

Neoadjuvant Chemotherapy With Cisplatin Up‐Regulates GSDMD to Enhance Oral Squamous Cell Carcinoma Metastasis Through MMP14‐Mediated EMT Activation

Advanced Science, EarlyView.
Oral squamous cell carcinoma cells exhibit upregulated expression of GSDMD upon exposure to low‐dose cisplatin chemotherapy, which subsequently interacts with MMP14 through its N‐terminal domain, activating the epithelial‒mesenchymal transition (EMT) process and promoting the lymph node metastasis of oral squamous cell carcinoma.
Zixian Huang, Qiming Jiang, Qianyu Zhang, Nan Lu, Xi Rui, Rui Chen, Yan Wang, Yuepeng Wang, Xiaoding Xu, Zhiquan Huang   +9 more
wiley   +1 more source

Fractal perspective of superquadratic functions with generalized probability estimations. [PDF]

PLoS One
Butt SI, Khan D, Seol Y.
europepmc   +1 more source

Flexible Regulation of Optical Properties Based on Structure Size‐Driven Intermolecular Interactions for Phototherapy

Advanced Science, EarlyView.
Herein, ACQ@AIE bimolecular systems are developed by noncovalently combining an aggregated‐caused quenching (ACQ) molecule with three aggregated‐induced emission (AIE) molecules. Differentials in structural size drive different patterns of intermolecular interactions, leading to distinct and tunable optical properties.
Zhichao Gong, Guangbo Kang, Yu Cao, Jiachen Pan, Xuejiao Rong, Xiaobing Du, Danping Zhang, He Huang, Shuxian Meng   +8 more
wiley   +1 more source

Detecting Signatures of Criticality Using Divergence Rate. [PDF]

Entropy (Basel)
Chan T, Soh W, Hillar C.
europepmc   +1 more source

Testosterone Delays Bone Microstructural Destruction via Osteoblast‐Androgen Receptor‐Mediated Upregulation of Tenascin‐C

Advanced Science, EarlyView.
This study reveals that Testosterone–Androgen Receptor signaling delays elderly male bone destruction by upregulation of the osteoblastic extracellular tenascin‐C (TNC). The osteoprotective effect of fibrinogen C‐terminus of TNC is demonstrated in male osteoporotic mice model that osteoblast‐specific Ar‐knockout, potentially via inhibition of ...
Yong Xie, Meng Pan, Zeyuan Zhang, Licheng Zhang, Haotian Liu, Xia Wang, William W Lu, Peifu Tang, Wei Ge   +8 more
wiley   +1 more source

Quantum Electrodynamics from Quantum Cellular Automata, and the Tension Between Symmetry, Locality, and Positive Energy. [PDF]

Entropy (Basel)
Brun TA, Mlodinow L.
europepmc   +1 more source

HDAC6 and USP9X Control Glutamine Metabolism by Stabilizing GS to Promote Glioblastoma Tumorigenesis

Advanced Science, EarlyView.
Glioblastoma (GBM) growth relies on glutamine synthetase (GS), which is stabilized by histone deacetylase 6 (HDAC6) and deubiquitinated by ubiquitin‐specific peptidase 9, X‐linked (USP9X). HDAC6 promotes GS deacetylation, while USP9X removes its K48‐linked polyubiquitination, enhancing GS stability.
Go Woon Kim, Minhae Cha, Hien Thi My Ong, Jung Yoo, Yu Hyun Jeon, Sang Wu Lee, Soo Yeon Oh, Min‐Jung Kang, Youngsoo Kim, So Hee Kwon   +9 more
wiley   +1 more source

Some novel concepts of interval-valued q-rung orthopair fuzzy graphs and computational framework of fuzzy air conditioning system. [PDF]

PLoS One
Khan WA, Abbas S, Ahmed A, Pal M, Asif M, Khan MS.   +5 more
europepmc   +1 more source