Results 41 to 50 of about 469,093 (241)

Quantifying Uncertainty in Brain Network Measures using Bayesian Connectomics

Frontiers in Computational Neuroscience, 2014
The wiring diagram of the human brain can be described in terms of graph measures that characterize structural regularities. These measures require an estimate of whole-brain structural connectivity for which one may resort to deterministic or ...
Ronald Johannes Janssen, Max eHinne, Max eHinne, Tom eHeskes, Marcel A.J. Van Gerven   +4 more
doaj   +1 more source

Automorphism Groups of Geometrically Represented Graphs [PDF]

, 2015
We describe a technique to determine the automorphism group of a geometrically represented graph, by understanding the structure of the induced action on all geometric representations.
Klavík, Pavel, Zeman, Peter
core  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

On singular probability densities generated by extremal dynamics

, 2004
Extremal dynamics is the mechanism that drives the Bak-Sneppen model into a (self-organized) critical state, marked by a singular stationary probability density $p(x)$.
Bak, Boettcher, Bose, Caldarelli, Dickman, Dickman, Donangelo, Dorogovtsev, Drossel, Felici, Grassberger, Guilherme J.M. Garcia, Head, Head, Li, Marsili, Maslov, Meester, Mikeska, Paczuski, Paczuski, Pismak, Rios, Ronald Dickman   +23 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Time estimation and beta segregation: An EEG study and graph theoretical approach. [PDF]

PLoS ONE, 2018
Elucidation of the neural correlates of time perception constitutes an important research topic in cognitive neuroscience. The focus to date has been on durations in the millisecond to seconds range, but here we used electroencephalography (EEG) to ...
Amir Hossein Ghaderi, Shadi Moradkhani, Arvin Haghighatfard, Fatemeh Akrami, Zahra Khayyer, Fuat Balcı   +5 more
doaj   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

Functional network of contextual and temporal memory has increased amygdala centrality and connectivity with the retrosplenial cortex, thalamus, and hippocampus

Scientific Reports, 2023
In fear conditioning with time intervals between the conditioned (CS) and unconditioned (US) stimuli, a neural representation of the CS must be maintained over time to be associated with the later US.
Thays Brenner Santos, Juliana Carlota Kramer-Soares, Cesar Augusto de Oliveira Coelho, Maria Gabriela Menezes Oliveira   +3 more
doaj   +1 more source

A survey on algorithmic aspects of modular decomposition

, 2009
The modular decomposition is a technique that applies but is not restricted to graphs. The notion of module naturally appears in the proofs of many graph theoretical theorems. Computing the modular decomposition tree is an important preprocessing step to
Habib, Michel, Paul, Christophe
core   +3 more sources

Menthol‐like cooling compounds, including (R)‐(‐)‐carvone, inhibit the human bitter taste receptors for saccharin and acesulfame K

FEBS Open Bio, EarlyView.
We report that some menthol‐like cooling compounds, including (R)‐(‐)‐carvone, act as inhibitors of TAS2R31 and TAS2R43, which are taste receptors responsible for the intrinsic bitter aftertastes of saccharin and acesulfame K. However, there was little correlation between the intensity of the cooling sensation and the potency of bitterness inhibition ...
Miyuu Saito, Takumi Misaka
wiley   +1 more source