Results 221 to 230 of about 10,658,076 (388)

Randomized, Controlled Trial of an Intervention for Toddlers With Autism: The Early Start Denver Model

Pediatrics, 2010
G. Dawson, S. Rogers, J. Munson, Milani Smith, Jamie Winter, J. Greenson, Amy L. Donaldson, J. Varley   +7 more
semanticscholar   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Intervention studies to foster resilience - A systematic review and proposal for a resilience framework in future intervention studies.

Clinical Psychology Review, 2018
A. Chmitorz, A. Kunzler, I. Helmreich, O. Tüscher, R. Kalisch, T. Kubiak, M. Wessa, K. Lieb   +7 more
semanticscholar   +1 more source

Multimodal Embolization Spheres for Radiotherapy and Interventional Radiology Improvement

, 2019
Séverine Lechevallier, Thomas Lacornerie, Robin Garcia, Boris Guiu, Xavier Mirabel, Julien Santelli, Cyril Martinez, Marine Vincent, Daniel Cussac, Laurent Marescaux, Robert Mauricot, Marc Verelst   +11 more
openalex   +1 more source

Defective intervention effects, die! [PDF]

, 2001
Atkinson, M
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Understanding healthy eating and physical activity community-centred behaviour change interventions for underserved populations: A mixed methods rapid review. [PDF]

Br J Health Psychol
Marshall J, Minihane AM, Jong ST, Hanson S, Akter S, Garner N, Hardeman W.   +6 more
europepmc   +1 more source

Intervention in Central Asia [PDF]

, 1997
Shepherd, Monika
core   +1 more source

Interventional cardiology [PDF]

Current Paediatrics, 1997
openaire   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source