PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Training Pediatric Residents to Provide Smoking Cessation Counseling to Parents
The objective was to assess the effectiveness of a smoking cessation educational program on pediatric residents' counseling. Residents were randomly selected to receive the intervention.
Rebecca L. Collins +3 more
doaj +1 more source
Efficiency of Intervention Counseling Program on the Enhanced Psychological Well-being and Reduced Post-traumatic Stress Disorder Symptoms Among Syrian Women Refugee Survivors. [PDF]
Alsheikh Ali ASS.
europepmc +1 more source
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Background: Lifestyle modification is an important factor in promoting the health of middle-aged women. Therefore, this study aimed to determine the effect of telephone counseling on the nutritional status and physical activity of middle-aged women in ...
Behnaz Enjezab +3 more
doaj
Rasulullah Saw. Dan Prinsip-prinsip Konseling Islam [PDF]
The Prophet and the Principles of Islamic Counseling. From a professional perspective Islamic counseling is a recent origin and few scholars have addressed this area of study in a significant way.
Lubis, L. (Lahmuddin)
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Efektivitas konseling kelompok rasional emotif behavioral dalam mereduksi egosentrisme remaja [PDF]
The aim of the research is to test the effectiveness of rational emotive behavioral counseling in reducing adolescent egocentrism. It uses a quantitative-qualitative (mix methods) approach with a quasi experimental research non equivalent pretest – post ...
Cinthyawati Nur’aini, Windy
core
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Optimalization Model For The Promotion Of Tuberculosis Free Hidangan Ekonomi Kecil (HEK) Kampongs In Surakarta [PDF]
Intervention model comprising group education, counseling, and leaflet use for optimizing the promotion of Hidangan Ekonomi Kecil (HEK) kampongs as a strategy for the prevention and control of tuberculosis has not been implemented. Tuberculosis (TB) is a
Hanim, Diffah +3 more
core

