Results 121 to 130 of about 4,048,647 (310)

No Peace in the House: Witchcraft Accusations as an Old Woman\u27s Problem in Ghana [PDF]

, 2013
In Ghana, older women may be marginalized, abused, and even killed as witches. Media accounts imply this is common practice, mainly through stories of “witches camps” to which the accused may flee.
Crampton, Alexandra
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Development Traps and Development Policy Interventions.

Risks and Catastrophes Journal
Nowadays, development has become a natural part of our lives, the dynamics and types of which are the only things we tend to highlight and compare. This is why it may seem unusual that science has identified an anomaly in certain territorial units where there is a lack of development. This situation has been called the development trap. The development
openaire   +2 more sources

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

A Collaborative Approach to Co‐Creating Contact Confident, an Evidence‐Informed Tackle Safety and Technique Intervention for Coaches and Players in Rugby Union

European Journal of Sport Science
Training strategies to promote safe and effective tackle technique are an important target for injury prevention and enhancing performance across the rugby codes.
Anna Stodter, Katrina McDonald, Danielle Salmon, Janelle Romanchuk, Nic Evans, Des Ryan, Tamara Taylor, Faye Easton, Jock Peggie   +8 more
doaj   +1 more source

A Multi-Site Refinement Study of Taking Back Control Together, an Intervention to Support Parents Confronted with Childhood Cancer

Current Oncology
A child’s cancer diagnosis profoundly impacts the psychological well-being of parents. To alleviate parental distress, researchers developed Taking Back Control Together (TBCT), a manualized six-session program targeting individual problem-solving skills
Nikita Guarascio, Ariane Levesque, David Ogez, Valérie Marcil, Daniel Curnier, Véronique Bélanger, Émélie Rondeau, Katherine Péloquin, Caroline Laverdière, Raoul Santiago, Josée Brossard, Stéphanie Vairy, Serge Sultan, The TBCT-Québec Team   +13 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Beyond the current state of just-in-time adaptive interventions in mental health: a qualitative systematic review

Frontiers in Digital Health
BackgroundJust-In-Time Adaptive Interventions (JITAIs) are interventions designed to deliver timely tailored support by adjusting to changes in users' internal states and external contexts.
Claire R. van Genugten, Claire R. van Genugten, Melissa S. Y. Thong, Melissa S. Y. Thong, Melissa S. Y. Thong, Wouter van Ballegooijen, Wouter van Ballegooijen, Wouter van Ballegooijen, Annet M. Kleiboer, Annet M. Kleiboer, Donna Spruijt-Metz, Arnout C. Smit, Mirjam A. G. Sprangers, Mirjam A. G. Sprangers, Yannik Terhorst, Yannik Terhorst, Heleen Riper, Heleen Riper, Heleen Riper   +18 more
doaj   +1 more source

Politics and professionalism in community development: Examining intervention in the highlands of northern Thailand [PDF]

, 2009
It has been suggested that the practice of international development assistance is so deeply problematic that the only moral choice is to abandon the work altogether.
Mckinnon, Katharine Islay
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source